PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Spirodela polyrhiza
ARF Family
Species TF ID Description
Spipo0G0032200ARF family protein
Spipo0G0098000ARF family protein
Spipo0G0185600ARF family protein
Spipo12G0063000ARF family protein
Spipo13G0044400ARF family protein
Spipo16G0055200ARF family protein
Spipo1G0049900ARF family protein
Spipo1G0061100ARF family protein
Spipo26G0023100ARF family protein
Spipo26G0026500ARF family protein
Spipo4G0062300ARF family protein
Spipo4G0074800ARF family protein
Spipo5G0000900ARF family protein
Spipo7G0053900ARF family protein
Spipo8G0048600ARF family protein
Spipo9G0041600ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969