PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Spinacia oleracea
ERF Family
Species TF ID Description
Sp_005860_fgmk.t1ERF family protein
Sp_008990_hyhf.t1ERF family protein
Sp_011330_gdsx.t1ERF family protein
Sp_011340_ydgz.t1ERF family protein
Sp_020130_ktkn.t1ERF family protein
Sp_021340_itnu.t1ERF family protein
Sp_021550_mfzg.t1ERF family protein
Sp_023190_qsoe.t1ERF family protein
Sp_023380_jnpe.t1ERF family protein
Sp_024670_sfen.t1ERF family protein
Sp_025040_ugmt.t1ERF family protein
Sp_028240_stod.t1ERF family protein
Sp_031310_cdtc.t1ERF family protein
Sp_032200_gqrq.t1ERF family protein
Sp_032700_tnie.t1ERF family protein
Sp_039260_ugqa.t1ERF family protein
Sp_044440_eciy.t1ERF family protein
Sp_045150_yprq.t1ERF family protein
Sp_045160_xpnu.t1ERF family protein
Sp_052680_tmyq.t1ERF family protein
Sp_057210_wxdz.t1ERF family protein
Sp_061940_ygfc.t1ERF family protein
Sp_064760_qzuw.t1ERF family protein
Sp_066580_wmtd.t1ERF family protein
Sp_071040_wfjy.t1ERF family protein
Sp_072150_kztd.t1ERF family protein
Sp_072160_kwwr.t1ERF family protein
Sp_080630_ycdx.t1ERF family protein
Sp_084160_osow.t1ERF family protein
Sp_092180_xwwn.t1ERF family protein
Sp_092700_ujtc.t1ERF family protein
Sp_096080_jccu.t1ERF family protein
Sp_102430_hnfa.t1ERF family protein
Sp_103010_ortt.t1ERF family protein
Sp_104320_safu.t1ERF family protein
Sp_112560_upqa.t1ERF family protein
Sp_112720_jcmg.t1ERF family protein
Sp_112730_pauf.t1ERF family protein
Sp_116420_qnkp.t1ERF family protein
Sp_118540_mafx.t1ERF family protein
Sp_125230_eyow.t1ERF family protein
Sp_127920_qtcs.t1ERF family protein
Sp_128850_ukru.t1ERF family protein
Sp_129130_upzh.t1ERF family protein
Sp_129920_pdnh.t1ERF family protein
Sp_129930_dnqd.t1ERF family protein
Sp_134990_htfp.t1ERF family protein
Sp_141040_qmwp.t1ERF family protein
Sp_141110_tori.t1ERF family protein
Sp_141120_wkyd.t1ERF family protein
Sp_144730_qoik.t1ERF family protein
Sp_152170_wfqt.t1ERF family protein
Sp_153450_gmir.t1ERF family protein
Sp_162620_yeyg.t1ERF family protein
Sp_163540_ctfk.t1ERF family protein
Sp_166820_fchz.t1ERF family protein
Sp_168300_azsd.t1ERF family protein
Sp_172040_pmpz.t1ERF family protein
Sp_172040_pmpz.t2ERF family protein
Sp_172920_ctky.t1ERF family protein
Sp_173960_qnfi.t1ERF family protein
Sp_188360_cegd.t1ERF family protein
Sp_203440_eqwf.t1ERF family protein
Sp_207030_ucfs.t1ERF family protein
Sp_213500_xoxo.t1ERF family protein
Sp_214490_exqc.t1ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102