PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Salvia miltiorrhiza
bZIP Family
Species TF ID Description
SMil_00000233-RA_SalvbZIP family protein
SMil_00001780-RA_SalvbZIP family protein
SMil_00001946-RA_SalvbZIP family protein
SMil_00003402-RA_SalvbZIP family protein
SMil_00003681-RA_SalvbZIP family protein
SMil_00003821-RA_SalvbZIP family protein
SMil_00004488-RA_SalvbZIP family protein
SMil_00004626-RA_SalvbZIP family protein
SMil_00005206-RA_SalvbZIP family protein
SMil_00005785-RA_SalvbZIP family protein
SMil_00005852-RA_SalvbZIP family protein
SMil_00006239-RA_SalvbZIP family protein
SMil_00006418-RA_SalvbZIP family protein
SMil_00006531-RA_SalvbZIP family protein
SMil_00007000-RA_SalvbZIP family protein
SMil_00007005-RA_SalvbZIP family protein
SMil_00007088-RA_SalvbZIP family protein
SMil_00007265-RA_SalvbZIP family protein
SMil_00007326-RA_SalvbZIP family protein
SMil_00007329-RA_SalvbZIP family protein
SMil_00007330-RA_SalvbZIP family protein
SMil_00008313-RA_SalvbZIP family protein
SMil_00008616-RA_SalvbZIP family protein
SMil_00008835-RA_SalvbZIP family protein
SMil_00009035-RA_SalvbZIP family protein
SMil_00009234-RA_SalvbZIP family protein
SMil_00009264-RA_SalvbZIP family protein
SMil_00010240-RA_SalvbZIP family protein
SMil_00010496-RA_SalvbZIP family protein
SMil_00010896-RA_SalvbZIP family protein
SMil_00011094-RA_SalvbZIP family protein
SMil_00011337-RA_SalvbZIP family protein
SMil_00012462-RA_SalvbZIP family protein
SMil_00012823-RA_SalvbZIP family protein
SMil_00013001-RA_SalvbZIP family protein
SMil_00013647-RA_SalvbZIP family protein
SMil_00014068-RA_SalvbZIP family protein
SMil_00015267-RA_SalvbZIP family protein
SMil_00015775-RA_SalvbZIP family protein
SMil_00016149-RA_SalvbZIP family protein
SMil_00017312-RA_SalvbZIP family protein
SMil_00017716-RA_SalvbZIP family protein
SMil_00018706-RA_SalvbZIP family protein
SMil_00018756-RA_SalvbZIP family protein
SMil_00019310-RA_SalvbZIP family protein
SMil_00020197-RA_SalvbZIP family protein
SMil_00020310-RA_SalvbZIP family protein
SMil_00020892-RA_SalvbZIP family protein
SMil_00022226-RA_SalvbZIP family protein
SMil_00022961-RA_SalvbZIP family protein
SMil_00024733-RA_SalvbZIP family protein
SMil_00025053-RA_SalvbZIP family protein
SMil_00025306-RA_SalvbZIP family protein
SMil_00025380-RA_SalvbZIP family protein
SMil_00025976-RA_SalvbZIP family protein
SMil_00026032-RA_SalvbZIP family protein
SMil_00026861-RA_SalvbZIP family protein
SMil_00026906-RA_SalvbZIP family protein
SMil_00027732-RA_SalvbZIP family protein
SMil_00027858-RA_SalvbZIP family protein
SMil_00028974-RA_SalvbZIP family protein
SMil_00029564-RA_SalvbZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833