PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Salvia miltiorrhiza
WRKY Family
Species TF ID Description
SMil_00000123-RA_SalvWRKY family protein
SMil_00000447-RA_SalvWRKY family protein
SMil_00000667-RA_SalvWRKY family protein
SMil_00001124-RA_SalvWRKY family protein
SMil_00001315-RA_SalvWRKY family protein
SMil_00001566-RA_SalvWRKY family protein
SMil_00001953-RA_SalvWRKY family protein
SMil_00002097-RA_SalvWRKY family protein
SMil_00002208-RA_SalvWRKY family protein
SMil_00002252-RA_SalvWRKY family protein
SMil_00002304-RA_SalvWRKY family protein
SMil_00002787-RA_SalvWRKY family protein
SMil_00003947-RA_SalvWRKY family protein
SMil_00004511-RA_SalvWRKY family protein
SMil_00004800-RA_SalvWRKY family protein
SMil_00005058-RA_SalvWRKY family protein
SMil_00005188-RA_SalvWRKY family protein
SMil_00005643-RA_SalvWRKY family protein
SMil_00006089-RA_SalvWRKY family protein
SMil_00006374-RA_SalvWRKY family protein
SMil_00006684-RA_SalvWRKY family protein
SMil_00006712-RA_SalvWRKY family protein
SMil_00006948-RA_SalvWRKY family protein
SMil_00006949-RA_SalvWRKY family protein
SMil_00007215-RA_SalvWRKY family protein
SMil_00007515-RA_SalvWRKY family protein
SMil_00007978-RA_SalvWRKY family protein
SMil_00008227-RA_SalvWRKY family protein
SMil_00008294-RA_SalvWRKY family protein
SMil_00009155-RA_SalvWRKY family protein
SMil_00009441-RA_SalvWRKY family protein
SMil_00009735-RA_SalvWRKY family protein
SMil_00010580-RA_SalvWRKY family protein
SMil_00012156-RA_SalvWRKY family protein
SMil_00012644-RA_SalvWRKY family protein
SMil_00012717-RA_SalvWRKY family protein
SMil_00012801-RA_SalvWRKY family protein
SMil_00013584-RA_SalvWRKY family protein
SMil_00014109-RA_SalvWRKY family protein
SMil_00016070-RA_SalvWRKY family protein
SMil_00016341-RA_SalvWRKY family protein
SMil_00016473-RA_SalvWRKY family protein
SMil_00016619-RA_SalvWRKY family protein
SMil_00017109-RA_SalvWRKY family protein
SMil_00017718-RA_SalvWRKY family protein
SMil_00017834-RA_SalvWRKY family protein
SMil_00017928-RA_SalvWRKY family protein
SMil_00019502-RA_SalvWRKY family protein
SMil_00019554-RA_SalvWRKY family protein
SMil_00020124-RA_SalvWRKY family protein
SMil_00020529-RA_SalvWRKY family protein
SMil_00020713-RA_SalvWRKY family protein
SMil_00020963-RA_SalvWRKY family protein
SMil_00021799-RA_SalvWRKY family protein
SMil_00021820-RA_SalvWRKY family protein
SMil_00021978-RA_SalvWRKY family protein
SMil_00022052-RA_SalvWRKY family protein
SMil_00022172-RA_SalvWRKY family protein
SMil_00022278-RA_SalvWRKY family protein
SMil_00022653-RA_SalvWRKY family protein
SMil_00023008-RA_SalvWRKY family protein
SMil_00023121-RA_SalvWRKY family protein
SMil_00023213-RA_SalvWRKY family protein
SMil_00023584-RA_SalvWRKY family protein
SMil_00023985-RA_SalvWRKY family protein
SMil_00025719-RA_SalvWRKY family protein
SMil_00026473-RA_SalvWRKY family protein
SMil_00026533-RA_SalvWRKY family protein
SMil_00026607-RA_SalvWRKY family protein
SMil_00027044-RA_SalvWRKY family protein
SMil_00027708-RA_SalvWRKY family protein
SMil_00028363-RA_SalvWRKY family protein
SMil_00028452-RA_SalvWRKY family protein
SMil_00028695-RA_SalvWRKY family protein
SMil_00029285-RA_SalvWRKY family protein
SMil_00029939-RA_SalvWRKY family protein
SMil_00029962-RA_SalvWRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701