PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Salvia miltiorrhiza
ARF Family
Species TF ID Description
SMil_00000332-RA_SalvARF family protein
SMil_00002054-RA_SalvARF family protein
SMil_00003923-RA_SalvARF family protein
SMil_00007048-RA_SalvARF family protein
SMil_00011004-RA_SalvARF family protein
SMil_00011552-RA_SalvARF family protein
SMil_00011716-RA_SalvARF family protein
SMil_00011783-RA_SalvARF family protein
SMil_00011888-RA_SalvARF family protein
SMil_00012294-RA_SalvARF family protein
SMil_00016549-RA_SalvARF family protein
SMil_00017439-RA_SalvARF family protein
SMil_00020906-RA_SalvARF family protein
SMil_00022205-RA_SalvARF family protein
SMil_00028807-RA_SalvARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969