PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Sisymbrium irio
TCP Family
Species TF ID Description
676700830TCP family protein
676708942TCP family protein
676709390TCP family protein
676709550TCP family protein
676716680TCP family protein
676720890TCP family protein
676722094TCP family protein
676724798TCP family protein
676729414TCP family protein
676729508TCP family protein
676730938TCP family protein
676733166TCP family protein
676734554TCP family protein
676740086TCP family protein
676744174TCP family protein
676744398TCP family protein
676751404TCP family protein
676756794TCP family protein
676759808TCP family protein
676760292TCP family protein
676784608TCP family protein
676786474TCP family protein
676792470TCP family protein
676792582TCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426