PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Sisymbrium irio
ERF Family
Species TF ID Description
676700762ERF family protein
676703602ERF family protein
676704276ERF family protein
676708478ERF family protein
676708480ERF family protein
676708482ERF family protein
676708970ERF family protein
676709324ERF family protein
676709604ERF family protein
676710060ERF family protein
676710088ERF family protein
676712918ERF family protein
676714314ERF family protein
676714868ERF family protein
676714984ERF family protein
676715074ERF family protein
676717412ERF family protein
676719318ERF family protein
676721228ERF family protein
676723854ERF family protein
676725400ERF family protein
676725436ERF family protein
676725992ERF family protein
676726726ERF family protein
676727376ERF family protein
676727984ERF family protein
676728418ERF family protein
676728420ERF family protein
676728982ERF family protein
676729494ERF family protein
676729656ERF family protein
676729658ERF family protein
676730070ERF family protein
676730126ERF family protein
676731834ERF family protein
676731848ERF family protein
676733108ERF family protein
676734676ERF family protein
676734940ERF family protein
676735064ERF family protein
676735080ERF family protein
676735216ERF family protein
676735584ERF family protein
676735616ERF family protein
676736794ERF family protein
676736816ERF family protein
676737322ERF family protein
676737450ERF family protein
676739250ERF family protein
676739978ERF family protein
676740962ERF family protein
676743108ERF family protein
676743310ERF family protein
676744004ERF family protein
676744260ERF family protein
676744320ERF family protein
676744712ERF family protein
676745738ERF family protein
676746666ERF family protein
676746808ERF family protein
676747492ERF family protein
676747744ERF family protein
676748562ERF family protein
676749128ERF family protein
676749302ERF family protein
676750132ERF family protein
676751122ERF family protein
676751828ERF family protein
676751894ERF family protein
676752082ERF family protein
676752122ERF family protein
676752214ERF family protein
676752310ERF family protein
676753546ERF family protein
676753590ERF family protein
676753848ERF family protein
676753914ERF family protein
676754864ERF family protein
676755244ERF family protein
676755540ERF family protein
676755556ERF family protein
676755594ERF family protein
676757812ERF family protein
676758536ERF family protein
676760434ERF family protein
676760522ERF family protein
676761356ERF family protein
676761358ERF family protein
676761362ERF family protein
676762966ERF family protein
676763008ERF family protein
676766060ERF family protein
676766702ERF family protein
676770562ERF family protein
676772302ERF family protein
676773044ERF family protein
676774526ERF family protein
676774528ERF family protein
676774626ERF family protein
676775262ERF family protein
676775708ERF family protein
676776668ERF family protein
676777462ERF family protein
676777512ERF family protein
676777558ERF family protein
676779274ERF family protein
676779306ERF family protein
676780860ERF family protein
676780942ERF family protein
676781674ERF family protein
676782726ERF family protein
676783708ERF family protein
676784544ERF family protein
676784640ERF family protein
676785680ERF family protein
676785970ERF family protein
676786386ERF family protein
676787974ERF family protein
676788210ERF family protein
676789678ERF family protein
676789716ERF family protein
676790596ERF family protein
676792602ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102