PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Sesamum indicum
WOX Family
Species TF ID Description
XP_011069676.1WOX family protein
XP_011074399.1WOX family protein
XP_011074398.1WOX family protein
XP_011074397.1WOX family protein
XP_011089388.1WOX family protein
XP_011084246.1WOX family protein
XP_011100154.1WOX family protein
XP_011076726.1WOX family protein
XP_011077272.1WOX family protein
XP_011096377.1WOX family protein
XP_011096378.1WOX family protein
XP_011096379.1WOX family protein
XP_011096381.1WOX family protein
XP_011090087.1WOX family protein
XP_011086022.1WOX family protein
XP_011070619.1WOX family protein
XP_011075487.1WOX family protein
XP_011069976.1WOX family protein
XP_011079126.1WOX family protein
XP_011079125.1WOX family protein
XP_011099896.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401


The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590