PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Sesamum indicum
FAR1 Family
Species TF ID Description
XP_011071525.1FAR1 family protein
XP_011072087.1FAR1 family protein
XP_011072522.1FAR1 family protein
XP_011072523.1FAR1 family protein
XP_011073396.1FAR1 family protein
XP_011073397.1FAR1 family protein
XP_011073398.1FAR1 family protein
XP_011073399.1FAR1 family protein
XP_011073400.1FAR1 family protein
XP_011073401.1FAR1 family protein
XP_011073402.1FAR1 family protein
XP_011073403.1FAR1 family protein
XP_011073405.1FAR1 family protein
XP_011073406.1FAR1 family protein
XP_011073899.1FAR1 family protein
XP_011073900.1FAR1 family protein
XP_011073901.1FAR1 family protein
XP_011073902.1FAR1 family protein
XP_011078717.1FAR1 family protein
XP_011078718.1FAR1 family protein
XP_011078719.1FAR1 family protein
XP_011078720.1FAR1 family protein
XP_011078721.1FAR1 family protein
XP_011078722.1FAR1 family protein
XP_011078723.1FAR1 family protein
XP_011080506.1FAR1 family protein
XP_011080507.1FAR1 family protein
XP_011080545.1FAR1 family protein
XP_011082429.1FAR1 family protein
XP_011082430.1FAR1 family protein
XP_011085456.1FAR1 family protein
XP_011085457.1FAR1 family protein
XP_011087634.1FAR1 family protein
XP_011088828.1FAR1 family protein
XP_011088829.1FAR1 family protein
XP_011088830.1FAR1 family protein
XP_011089602.1FAR1 family protein
XP_011089603.1FAR1 family protein
XP_011089604.1FAR1 family protein
XP_011089606.1FAR1 family protein
XP_011089611.1FAR1 family protein
XP_011090244.1FAR1 family protein
XP_011090245.1FAR1 family protein
XP_011090246.1FAR1 family protein
XP_011090247.1FAR1 family protein
XP_011090829.1FAR1 family protein
XP_011090830.1FAR1 family protein
XP_011093602.1FAR1 family protein
XP_011093603.1FAR1 family protein
XP_011093605.1FAR1 family protein
XP_011093709.1FAR1 family protein
XP_011093710.1FAR1 family protein
XP_011093711.1FAR1 family protein
XP_011093713.1FAR1 family protein
XP_011093714.1FAR1 family protein
XP_011095923.1FAR1 family protein
XP_011096824.1FAR1 family protein
XP_011096826.1FAR1 family protein
XP_011096827.1FAR1 family protein
XP_011098324.1FAR1 family protein
XP_011098802.1FAR1 family protein
XP_011098803.1FAR1 family protein
XP_011098804.1FAR1 family protein
XP_011098805.1FAR1 family protein
XP_011100396.1FAR1 family protein
XP_011100397.1FAR1 family protein
XP_011100571.1FAR1 family protein
XP_011101183.1FAR1 family protein
XP_011101184.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885