Plant Transcription Factor Database
Previous version: v1.0, v2.0, v3.0
Raphanus raphanistrum
ARF Family
Species TF ID Description
RrC1226_p4ARF family protein
RrC126_p9ARF family protein
RrC15780_p1ARF family protein
RrC1835_p1ARF family protein
RrC20115_p2ARF family protein
RrC243_p5ARF family protein
RrC3261_p2ARF family protein
RrC3289_p2ARF family protein
RrC3401_p2ARF family protein
RrC3638_p2ARF family protein
RrC414_p2ARF family protein
RrC4660_p2ARF family protein
RrC5429_p1ARF family protein
RrC5488_p1ARF family protein
RrC62_p3ARF family protein
RrC7820_p1ARF family protein
RrC8501_p2ARF family protein
RrC8735_p1ARF family protein
RrC8969_p1ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969