PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Ricinus communis
WRKY Family
Species TF ID Description
27613.m000639WRKY family protein
27996.m000145WRKY family protein
28040.m000035WRKY family protein
28455.m000362WRKY family protein
28644.m000915WRKY family protein
28690.m000025WRKY family protein
28966.m000524WRKY family protein
29598.m000445WRKY family protein
29635.m000468WRKY family protein
29644.m000187WRKY family protein
29687.m000562WRKY family protein
29693.m002060WRKY family protein
29709.m001171WRKY family protein
29717.m000222WRKY family protein
29729.m002330WRKY family protein
29729.m002369WRKY family protein
29729.m002370WRKY family protein
29736.m002023WRKY family protein
29739.m003586WRKY family protein
29767.m000208WRKY family protein
29771.m000072WRKY family protein
29805.m001504WRKY family protein
29820.m001029WRKY family protein
29822.m003484WRKY family protein
29842.m003555WRKY family protein
29848.m004464WRKY family protein
29848.m004539WRKY family protein
29848.m004544WRKY family protein
29848.m004545WRKY family protein
29883.m002008WRKY family protein
29889.m003321WRKY family protein
29915.m000479WRKY family protein
29929.m004587WRKY family protein
29929.m004624WRKY family protein
29949.m000123WRKY family protein
29990.m000497WRKY family protein
30010.m000675WRKY family protein
30026.m001461WRKY family protein
30064.m000506WRKY family protein
30076.m004548WRKY family protein
30076.m004623WRKY family protein
30076.m004648WRKY family protein
30131.m006850WRKY family protein
30147.m014087WRKY family protein
30147.m014474WRKY family protein
30169.m006533WRKY family protein
30169.m006581WRKY family protein
30170.m013832WRKY family protein
30174.m008651WRKY family protein
30174.m008663WRKY family protein
30174.m008669WRKY family protein
30174.m009135WRKY family protein
30174.m009166WRKY family protein
30190.m010814WRKY family protein
30190.m010908WRKY family protein
30190.m011276WRKY family protein
30190.m011278WRKY family protein
43951.m000016WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701