PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Ricinus communis
ARF Family
Species TF ID Description
27494.m000045ARF family protein
27538.m000327ARF family protein
29599.m000177ARF family protein
29609.m000586ARF family protein
29609.m000587ARF family protein
29739.m003713ARF family protein
29742.m001397ARF family protein
29769.m000463ARF family protein
29900.m001540ARF family protein
29908.m005953ARF family protein
30068.m002516ARF family protein
30078.m002329ARF family protein
30111.m000734ARF family protein
30128.m008545ARF family protein
30147.m014418ARF family protein
30170.m014161ARF family protein
30185.m000956ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969