PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Prunus mume
FAR1 Family
Species TF ID Description
XP_008218478.1FAR1 family protein
XP_008218670.1FAR1 family protein
XP_008219518.1FAR1 family protein
XP_008219733.2FAR1 family protein
XP_008220898.1FAR1 family protein
XP_008222476.1FAR1 family protein
XP_008222477.1FAR1 family protein
XP_008222480.1FAR1 family protein
XP_008223038.1FAR1 family protein
XP_008223039.1FAR1 family protein
XP_008223294.1FAR1 family protein
XP_008225874.1FAR1 family protein
XP_008225875.1FAR1 family protein
XP_008225876.1FAR1 family protein
XP_008225877.1FAR1 family protein
XP_008225878.1FAR1 family protein
XP_008225879.1FAR1 family protein
XP_008227430.1FAR1 family protein
XP_008227616.2FAR1 family protein
XP_008227658.1FAR1 family protein
XP_008228073.1FAR1 family protein
XP_008228719.2FAR1 family protein
XP_008229651.1FAR1 family protein
XP_008229653.1FAR1 family protein
XP_008229654.1FAR1 family protein
XP_008229655.1FAR1 family protein
XP_008229656.1FAR1 family protein
XP_008229713.1FAR1 family protein
XP_008229916.1FAR1 family protein
XP_008231884.1FAR1 family protein
XP_008231885.1FAR1 family protein
XP_008233197.1FAR1 family protein
XP_008234281.1FAR1 family protein
XP_008234282.1FAR1 family protein
XP_008234547.1FAR1 family protein
XP_008234548.1FAR1 family protein
XP_008234549.1FAR1 family protein
XP_008235784.1FAR1 family protein
XP_008235836.1FAR1 family protein
XP_008235882.1FAR1 family protein
XP_008235883.1FAR1 family protein
XP_008235884.1FAR1 family protein
XP_008235933.1FAR1 family protein
XP_008237257.1FAR1 family protein
XP_008237259.1FAR1 family protein
XP_008237306.1FAR1 family protein
XP_008237973.1FAR1 family protein
XP_008238368.1FAR1 family protein
XP_008238706.1FAR1 family protein
XP_008240644.1FAR1 family protein
XP_008240714.2FAR1 family protein
XP_008241736.1FAR1 family protein
XP_008241737.1FAR1 family protein
XP_008241738.1FAR1 family protein
XP_008241739.1FAR1 family protein
XP_008242120.2FAR1 family protein
XP_008243431.1FAR1 family protein
XP_008244440.1FAR1 family protein
XP_008244497.1FAR1 family protein
XP_008245175.1FAR1 family protein
XP_016647407.1FAR1 family protein
XP_016647930.1FAR1 family protein
XP_016647975.1FAR1 family protein
XP_016647976.1FAR1 family protein
XP_016648093.1FAR1 family protein
XP_016648094.1FAR1 family protein
XP_016648403.1FAR1 family protein
XP_016648404.1FAR1 family protein
XP_016648843.1FAR1 family protein
XP_016649080.1FAR1 family protein
XP_016649292.1FAR1 family protein
XP_016649472.1FAR1 family protein
XP_016649570.1FAR1 family protein
XP_016649709.1FAR1 family protein
XP_016649765.1FAR1 family protein
XP_016650496.1FAR1 family protein
XP_016650634.1FAR1 family protein
XP_016650635.1FAR1 family protein
XP_016651010.1FAR1 family protein
XP_016651478.1FAR1 family protein
XP_016652765.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885