PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Pseudotsuga menziesii
WRKY Family
Species TF ID Description
PSME_00000342-RAWRKY family protein
PSME_00001545-RAWRKY family protein
PSME_00001973-RAWRKY family protein
PSME_00001979-RAWRKY family protein
PSME_00004738-RAWRKY family protein
PSME_00008606-RAWRKY family protein
PSME_00010621-RAWRKY family protein
PSME_00010717-RAWRKY family protein
PSME_00011301-RAWRKY family protein
PSME_00012259-RAWRKY family protein
PSME_00013774-RAWRKY family protein
PSME_00015239-RAWRKY family protein
PSME_00016606-RAWRKY family protein
PSME_00018337-RAWRKY family protein
PSME_00021158-RAWRKY family protein
PSME_00021940-RAWRKY family protein
PSME_00022813-RAWRKY family protein
PSME_00023520-RAWRKY family protein
PSME_00023521-RAWRKY family protein
PSME_00023522-RAWRKY family protein
PSME_00024308-RAWRKY family protein
PSME_00024309-RAWRKY family protein
PSME_00025597-RAWRKY family protein
PSME_00028840-RAWRKY family protein
PSME_00028885-RAWRKY family protein
PSME_00028886-RAWRKY family protein
PSME_00030013-RAWRKY family protein
PSME_00030014-RAWRKY family protein
PSME_00032293-RAWRKY family protein
PSME_00032678-RAWRKY family protein
PSME_00033470-RAWRKY family protein
PSME_00033789-RAWRKY family protein
PSME_00034008-RAWRKY family protein
PSME_00035158-RAWRKY family protein
PSME_00035159-RAWRKY family protein
PSME_00035861-RAWRKY family protein
PSME_00035862-RAWRKY family protein
PSME_00036209-RAWRKY family protein
PSME_00036210-RAWRKY family protein
PSME_00036434-RAWRKY family protein
PSME_00037224-RAWRKY family protein
PSME_00037572-RAWRKY family protein
PSME_00037573-RAWRKY family protein
PSME_00037996-RAWRKY family protein
PSME_00039002-RAWRKY family protein
PSME_00039003-RAWRKY family protein
PSME_00039098-RAWRKY family protein
PSME_00039099-RAWRKY family protein
PSME_00040311-RAWRKY family protein
PSME_00040625-RAWRKY family protein
PSME_00041150-RAWRKY family protein
PSME_00041689-RAWRKY family protein
PSME_00042021-RAWRKY family protein
PSME_00042113-RAWRKY family protein
PSME_00042449-RAWRKY family protein
PSME_00042944-RAWRKY family protein
PSME_00043147-RAWRKY family protein
PSME_00043733-RAWRKY family protein
PSME_00044492-RAWRKY family protein
PSME_00046495-RAWRKY family protein
PSME_00046716-RAWRKY family protein
PSME_00047222-RAWRKY family protein
PSME_00048506-RAWRKY family protein
PSME_00048777-RAWRKY family protein
PSME_00049059-RAWRKY family protein
PSME_00049501-RAWRKY family protein
PSME_00049648-RAWRKY family protein
PSME_00049813-RAWRKY family protein
PSME_00050229-RAWRKY family protein
PSME_00050268-RAWRKY family protein
PSME_00050907-RAWRKY family protein
PSME_00051019-RAWRKY family protein
PSME_00051212-RAWRKY family protein
PSME_00051520-RAWRKY family protein
PSME_00051522-RAWRKY family protein
PSME_00052260-RAWRKY family protein
PSME_00052512-RAWRKY family protein
PSME_00053369-RAWRKY family protein
PSME_00053709-RAWRKY family protein
PSME_00054708-RAWRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701