Plant Transcription Factor Database
Previous version: v1.0, v2.0, v3.0
Pseudotsuga menziesii
G2-like Family
Species TF ID Description
PSME_00001021-RAG2-like family protein
PSME_00001023-RAG2-like family protein
PSME_00001285-RAG2-like family protein
PSME_00002495-RAG2-like family protein
PSME_00003147-RAG2-like family protein
PSME_00003148-RAG2-like family protein
PSME_00003323-RAG2-like family protein
PSME_00004827-RAG2-like family protein
PSME_00005591-RAG2-like family protein
PSME_00006691-RAG2-like family protein
PSME_00007589-RAG2-like family protein
PSME_00007590-RAG2-like family protein
PSME_00009501-RAG2-like family protein
PSME_00015668-RAG2-like family protein
PSME_00016111-RAG2-like family protein
PSME_00017877-RAG2-like family protein
PSME_00018297-RAG2-like family protein
PSME_00018334-RAG2-like family protein
PSME_00018346-RAG2-like family protein
PSME_00021090-RAG2-like family protein
PSME_00021152-RAG2-like family protein
PSME_00022449-RAG2-like family protein
PSME_00022558-RAG2-like family protein
PSME_00024669-RAG2-like family protein
PSME_00028751-RAG2-like family protein
PSME_00029717-RAG2-like family protein
PSME_00031433-RAG2-like family protein
PSME_00033607-RAG2-like family protein
PSME_00033877-RAG2-like family protein
PSME_00036264-RAG2-like family protein
PSME_00038752-RAG2-like family protein
PSME_00039378-RAG2-like family protein
PSME_00039482-RAG2-like family protein
PSME_00040545-RAG2-like family protein
PSME_00040944-RAG2-like family protein
PSME_00041717-RAG2-like family protein
PSME_00043158-RAG2-like family protein
PSME_00043566-RAG2-like family protein
PSME_00043647-RAG2-like family protein
PSME_00045457-RAG2-like family protein
PSME_00046346-RAG2-like family protein
PSME_00051778-RAG2-like family protein
PSME_00053252-RAG2-like family protein
PSME_00055202-RAG2-like family protein
G2-like Family Introduction

The GLK proteins are members of the recently categorized GARP superfamily of transcription factors (Riechmann et al., 2000) defined by G2 in maize; the Arabidopsis RESPONSE REGULATOR-B (ARR-B) proteins (Imamura et al., 1999); and the PHOSPHATE STARVATION RESPONSE1 (PSR1) protein of Chlamydomonas (Wykoff et al., 1999). In the case of G2, three of the four defining features of most transcription factors have been verified experimentally in heterologous systems. G2 is nuclearlocalized (Hall et al., 1998), is able to transactivate reporter gene expression, and can both homo-dimerize and heterodimerize with ZmGLK1 (Rossini et al., 2001). DNA-binding activity of GLK proteins has yet to be demonstrated,however, the putative DNA-binding domain is highly conserved with domains in other GARP proteins such as ARR1 and ARR2 (Riechmann et al., 2000). Notably, ARR1 and ARR2 have been shown to bind DNA (Sakai et al.,2000), thus it is likely that GLK proteins act as transcriptional regulators of chloroplast development.

The GLK proteins are members of the GARP superfamily of transcription factors, and phylogenetic analysis demonstrates that the maize, rice and Arabidopsis GLK gene pairs comprise a distinct group within the GARP superfamily. Further phylogenetic analysis suggests that the gene pairs arose through separate duplication events in the monocot and dicot lineages. As in rice, AtGLK1 and AtGLK2 are expressed in partially overlapping domains in photosynthetic tissue. GLK genes therefore regulate chloroplast development in diverse plant species.

Fitter DW, Martin DJ, Copley MJ, Scotland RW, Langdale JA.
GLK gene pairs regulate chloroplast development in diverse plant species.
Plant J. 2002 Sep;31(6):713-27.
PMID: 12220263