PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Pseudotsuga menziesii
ARF Family
Species TF ID Description
PSME_00020341-RAARF family protein
PSME_00022730-RAARF family protein
PSME_00023239-RAARF family protein
PSME_00028879-RAARF family protein
PSME_00035612-RAARF family protein
PSME_00037288-RAARF family protein
PSME_00047903-RAARF family protein
PSME_00050564-RAARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969