PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Phyllostachys heterocycla
bHLH Family
Species TF ID Description
PH01000002G3170bHLH family protein
PH01000004G1210bHLH family protein
PH01000005G3020bHLH family protein
PH01000014G0340bHLH family protein
PH01000019G1940bHLH family protein
PH01000026G0570bHLH family protein
PH01000030G0570bHLH family protein
PH01000030G1780bHLH family protein
PH01000031G0250bHLH family protein
PH01000032G0100bHLH family protein
PH01000038G2070bHLH family protein
PH01000039G0180bHLH family protein
PH01000045G2030bHLH family protein
PH01000050G0500bHLH family protein
PH01000059G2190bHLH family protein
PH01000063G1010bHLH family protein
PH01000065G2010bHLH family protein
PH01000068G1510bHLH family protein
PH01000068G1560bHLH family protein
PH01000069G1480bHLH family protein
PH01000089G0980bHLH family protein
PH01000098G0880bHLH family protein
PH01000104G0210bHLH family protein
PH01000105G0060bHLH family protein
PH01000107G0310bHLH family protein
PH01000110G0500bHLH family protein
PH01000117G0310bHLH family protein
PH01000120G1730bHLH family protein
PH01000150G0690bHLH family protein
PH01000165G1370bHLH family protein
PH01000170G0120bHLH family protein
PH01000178G0330bHLH family protein
PH01000179G0630bHLH family protein
PH01000179G0720bHLH family protein
PH01000193G0970bHLH family protein
PH01000197G0410bHLH family protein
PH01000201G0400bHLH family protein
PH01000225G0520bHLH family protein
PH01000255G0320bHLH family protein
PH01000260G1020bHLH family protein
PH01000260G1030bHLH family protein
PH01000264G0040bHLH family protein
PH01000286G0980bHLH family protein
PH01000300G0590bHLH family protein
PH01000309G0940bHLH family protein
PH01000323G0020bHLH family protein
PH01000323G0290bHLH family protein
PH01000331G0630bHLH family protein
PH01000338G1040bHLH family protein
PH01000348G0830bHLH family protein
PH01000355G1080bHLH family protein
PH01000385G0170bHLH family protein
PH01000390G0500bHLH family protein
PH01000397G0940bHLH family protein
PH01000405G0640bHLH family protein
PH01000431G0060bHLH family protein
PH01000448G0580bHLH family protein
PH01000519G0840bHLH family protein
PH01000530G0190bHLH family protein
PH01000534G0360bHLH family protein
PH01000595G0290bHLH family protein
PH01000599G0590bHLH family protein
PH01000626G0180bHLH family protein
PH01000655G0140bHLH family protein
PH01000656G0510bHLH family protein
PH01000679G0760bHLH family protein
PH01000724G0700bHLH family protein
PH01000732G0100bHLH family protein
PH01000740G0150bHLH family protein
PH01000754G0430bHLH family protein
PH01000773G0410bHLH family protein
PH01000783G0010bHLH family protein
PH01000783G0460bHLH family protein
PH01000786G0600bHLH family protein
PH01000803G0670bHLH family protein
PH01000941G0090bHLH family protein
PH01000943G0430bHLH family protein
PH01000960G0260bHLH family protein
PH01001042G0210bHLH family protein
PH01001045G0070bHLH family protein
PH01001051G0170bHLH family protein
PH01001067G0210bHLH family protein
PH01001092G0280bHLH family protein
PH01001110G0250bHLH family protein
PH01001119G0330bHLH family protein
PH01001129G0100bHLH family protein
PH01001137G0080bHLH family protein
PH01001155G0390bHLH family protein
PH01001158G0670bHLH family protein
PH01001159G0170bHLH family protein
PH01001160G0380bHLH family protein
PH01001228G0390bHLH family protein
PH01001260G0280bHLH family protein
PH01001302G0050bHLH family protein
PH01001302G0300bHLH family protein
PH01001385G0290bHLH family protein
PH01001389G0560bHLH family protein
PH01001400G0040bHLH family protein
PH01001446G0150bHLH family protein
PH01001461G0130bHLH family protein
PH01001463G0020bHLH family protein
PH01001480G0090bHLH family protein
PH01001525G0260bHLH family protein
PH01001538G0490bHLH family protein
PH01001554G0110bHLH family protein
PH01001562G0090bHLH family protein
PH01001571G0100bHLH family protein
PH01001576G0310bHLH family protein
PH01001578G0450bHLH family protein
PH01001599G0160bHLH family protein
PH01001641G0420bHLH family protein
PH01001671G0060bHLH family protein
PH01001678G0300bHLH family protein
PH01001759G0450bHLH family protein
PH01001857G0270bHLH family protein
PH01001876G0340bHLH family protein
PH01001986G0360bHLH family protein
PH01001999G0060bHLH family protein
PH01002021G0090bHLH family protein
PH01002160G0240bHLH family protein
PH01002260G0190bHLH family protein
PH01002346G0340bHLH family protein
PH01002420G0050bHLH family protein
PH01002508G0050bHLH family protein
PH01002550G0330bHLH family protein
PH01002584G0160bHLH family protein
PH01002623G0240bHLH family protein
PH01002627G0250bHLH family protein
PH01002636G0200bHLH family protein
PH01002657G0020bHLH family protein
PH01002677G0180bHLH family protein
PH01002725G0230bHLH family protein
PH01002779G0140bHLH family protein
PH01002804G0220bHLH family protein
PH01002918G0050bHLH family protein
PH01002919G0020bHLH family protein
PH01002972G0210bHLH family protein
PH01002972G0240bHLH family protein
PH01003119G0170bHLH family protein
PH01003206G0160bHLH family protein
PH01003334G0180bHLH family protein
PH01003422G0070bHLH family protein
PH01003449G0170bHLH family protein
PH01003462G0030bHLH family protein
PH01003717G0190bHLH family protein
PH01003751G0100bHLH family protein
PH01003768G0010bHLH family protein
PH01003790G0150bHLH family protein
PH01003862G0080bHLH family protein
PH01003883G0030bHLH family protein
PH01004066G0100bHLH family protein
PH01004323G0080bHLH family protein
PH01004440G0090bHLH family protein
PH01004715G0040bHLH family protein
PH01004728G0030bHLH family protein
PH01004870G0100bHLH family protein
PH01004959G0010bHLH family protein
PH01005012G0090bHLH family protein
PH01005069G0010bHLH family protein
PH01005158G0070bHLH family protein
PH01005189G0020bHLH family protein
PH01005423G0060bHLH family protein
PH01005548G0080bHLH family protein
PH01006153G0020bHLH family protein
PH01006362G0030bHLH family protein
PH01007980G0020bHLH family protein
PH01103680G0010bHLH family protein
PH01269246G0010bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250