PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Picea glauca
ERF Family
Species TF ID Description
Pgl000130ERF family protein
Pgl000562ERF family protein
Pgl001177ERF family protein
Pgl002207ERF family protein
Pgl002458ERF family protein
Pgl003560ERF family protein
Pgl003798ERF family protein
Pgl004467ERF family protein
Pgl004819ERF family protein
Pgl004973ERF family protein
Pgl005906ERF family protein
Pgl006566ERF family protein
Pgl006787ERF family protein
Pgl006996ERF family protein
Pgl007014ERF family protein
Pgl007095ERF family protein
Pgl007123ERF family protein
Pgl007133ERF family protein
Pgl007177ERF family protein
Pgl007289ERF family protein
Pgl007549ERF family protein
Pgl007596ERF family protein
Pgl008405ERF family protein
Pgl010162ERF family protein
Pgl010469ERF family protein
Pgl011023ERF family protein
Pgl012195ERF family protein
Pgl012969ERF family protein
Pgl013065ERF family protein
Pgl013686ERF family protein
Pgl014049ERF family protein
Pgl015908ERF family protein
Pgl016410ERF family protein
Pgl016508ERF family protein
Pgl016815ERF family protein
Pgl017560ERF family protein
Pgl017640ERF family protein
Pgl017726ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102