PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Phalaenopsis equestris
WRKY Family
Species TF ID Description
PEQU_00615WRKY family protein
PEQU_00834WRKY family protein
PEQU_00874WRKY family protein
PEQU_04552WRKY family protein
PEQU_04620WRKY family protein
PEQU_04739WRKY family protein
PEQU_05055WRKY family protein
PEQU_05824WRKY family protein
PEQU_06050WRKY family protein
PEQU_06415WRKY family protein
PEQU_06548WRKY family protein
PEQU_07027WRKY family protein
PEQU_07445WRKY family protein
PEQU_07550WRKY family protein
PEQU_07695WRKY family protein
PEQU_08336WRKY family protein
PEQU_08838WRKY family protein
PEQU_08905WRKY family protein
PEQU_09007WRKY family protein
PEQU_09206WRKY family protein
PEQU_09661WRKY family protein
PEQU_09833WRKY family protein
PEQU_11845WRKY family protein
PEQU_12090WRKY family protein
PEQU_12372WRKY family protein
PEQU_12845WRKY family protein
PEQU_12968WRKY family protein
PEQU_13284WRKY family protein
PEQU_13836WRKY family protein
PEQU_13851WRKY family protein
PEQU_13983WRKY family protein
PEQU_14261WRKY family protein
PEQU_14355WRKY family protein
PEQU_14366WRKY family protein
PEQU_15046WRKY family protein
PEQU_15396WRKY family protein
PEQU_16914WRKY family protein
PEQU_17589WRKY family protein
PEQU_17654WRKY family protein
PEQU_18052WRKY family protein
PEQU_18150WRKY family protein
PEQU_18252WRKY family protein
PEQU_18628WRKY family protein
PEQU_19129WRKY family protein
PEQU_22603WRKY family protein
PEQU_24418WRKY family protein
PEQU_24499WRKY family protein
PEQU_24500WRKY family protein
PEQU_24834WRKY family protein
PEQU_27196WRKY family protein
PEQU_27822WRKY family protein
PEQU_29266WRKY family protein
PEQU_29268WRKY family protein
PEQU_31437WRKY family protein
PEQU_32107WRKY family protein
PEQU_32427WRKY family protein
PEQU_32685WRKY family protein
PEQU_32690WRKY family protein
PEQU_34484WRKY family protein
PEQU_35078WRKY family protein
PEQU_37923WRKY family protein
PEQU_38269WRKY family protein
PEQU_38604WRKY family protein
PEQU_38634WRKY family protein
PEQU_38670WRKY family protein
PEQU_40300WRKY family protein
PEQU_40468WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701