PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Phalaenopsis equestris
FAR1 Family
Species TF ID Description
PEQU_00378FAR1 family protein
PEQU_00621FAR1 family protein
PEQU_00959FAR1 family protein
PEQU_01722FAR1 family protein
PEQU_04085FAR1 family protein
PEQU_04438FAR1 family protein
PEQU_05255FAR1 family protein
PEQU_05299FAR1 family protein
PEQU_06209FAR1 family protein
PEQU_06219FAR1 family protein
PEQU_06264FAR1 family protein
PEQU_06360FAR1 family protein
PEQU_06363FAR1 family protein
PEQU_07724FAR1 family protein
PEQU_07958FAR1 family protein
PEQU_08069FAR1 family protein
PEQU_09302FAR1 family protein
PEQU_09831FAR1 family protein
PEQU_10556FAR1 family protein
PEQU_10623FAR1 family protein
PEQU_11431FAR1 family protein
PEQU_12520FAR1 family protein
PEQU_13171FAR1 family protein
PEQU_14129FAR1 family protein
PEQU_14178FAR1 family protein
PEQU_15871FAR1 family protein
PEQU_16592FAR1 family protein
PEQU_17423FAR1 family protein
PEQU_17954FAR1 family protein
PEQU_18567FAR1 family protein
PEQU_19179FAR1 family protein
PEQU_19794FAR1 family protein
PEQU_20074FAR1 family protein
PEQU_20462FAR1 family protein
PEQU_20492FAR1 family protein
PEQU_21081FAR1 family protein
PEQU_21542FAR1 family protein
PEQU_21853FAR1 family protein
PEQU_21971FAR1 family protein
PEQU_22182FAR1 family protein
PEQU_22232FAR1 family protein
PEQU_22493FAR1 family protein
PEQU_22804FAR1 family protein
PEQU_23076FAR1 family protein
PEQU_23357FAR1 family protein
PEQU_23545FAR1 family protein
PEQU_23753FAR1 family protein
PEQU_23889FAR1 family protein
PEQU_23959FAR1 family protein
PEQU_24481FAR1 family protein
PEQU_25592FAR1 family protein
PEQU_26080FAR1 family protein
PEQU_26225FAR1 family protein
PEQU_27978FAR1 family protein
PEQU_28230FAR1 family protein
PEQU_28489FAR1 family protein
PEQU_29038FAR1 family protein
PEQU_29271FAR1 family protein
PEQU_29622FAR1 family protein
PEQU_30122FAR1 family protein
PEQU_30265FAR1 family protein
PEQU_30592FAR1 family protein
PEQU_30929FAR1 family protein
PEQU_32011FAR1 family protein
PEQU_32624FAR1 family protein
PEQU_32989FAR1 family protein
PEQU_33016FAR1 family protein
PEQU_33935FAR1 family protein
PEQU_33988FAR1 family protein
PEQU_34520FAR1 family protein
PEQU_34989FAR1 family protein
PEQU_35243FAR1 family protein
PEQU_35411FAR1 family protein
PEQU_35420FAR1 family protein
PEQU_35599FAR1 family protein
PEQU_35829FAR1 family protein
PEQU_37413FAR1 family protein
PEQU_37461FAR1 family protein
PEQU_38160FAR1 family protein
PEQU_38462FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885