PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Phalaenopsis equestris
ARF Family
Species TF ID Description
PEQU_00331ARF family protein
PEQU_03183ARF family protein
PEQU_03694ARF family protein
PEQU_03892ARF family protein
PEQU_08639ARF family protein
PEQU_09678ARF family protein
PEQU_10916ARF family protein
PEQU_14090ARF family protein
PEQU_14910ARF family protein
PEQU_15453ARF family protein
PEQU_19787ARF family protein
PEQU_26065ARF family protein
PEQU_32778ARF family protein
PEQU_33654ARF family protein
PEQU_36147ARF family protein
PEQU_36240ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969