Plant Transcription Factor Database
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Phoenix dactylifera
HSF Family
Species TF ID Description
PDK_30s1011221g001HSF family protein
PDK_30s1012181g002HSF family protein
PDK_30s1027561g002HSF family protein
PDK_30s1028391g001HSF family protein
PDK_30s1043311g005HSF family protein
PDK_30s1151651g002HSF family protein
PDK_30s65509193g001HSF family protein
PDK_30s660861g001HSF family protein
PDK_30s662861g009HSF family protein
PDK_30s679881g001HSF family protein
PDK_30s687281g002HSF family protein
PDK_30s711681g001HSF family protein
PDK_30s713921g001HSF family protein
PDK_30s774131g009HSF family protein
PDK_30s779791g002HSF family protein
PDK_30s901541g001HSF family protein
PDK_30s931581g002HSF family protein
PDK_30s941951g001HSF family protein
PDK_30s948451g002HSF family protein
HSF Family Introduction

Heat stress transcription factors (Hsfs) are the major regulators of the plant heat stress (hs) response. Sequencing of the Arabidopsis genome revealed the existence of 21 open-reading frames (ORFs) encoding putative Hsfs assigned to classes A-C. Here we present results of a functional genomics approach to the Arabidopsis Hsf family focused on the analysis of their C-terminal domains (CTDs) harboring conserved modules for their function as transcription factors and their intracellular localization. Using reporter assays in tobacco protoplasts and yeast as well as glutathione-S-transferase (GST) pull-down assays, we demonstrate that short peptide motifs enriched with aromatic and large hydrophobic amino acid (aa) residues embedded in an acidic surrounding (AHA motifs) are essential for transcriptional activity of class A Hsfs. In contrast to this, class B and C Hsfs lack AHA motifs and have no activator function on their own. We also provide evidence for the function of a leucine (Leu)-rich region centered around a conserved QMGΦL motif at the very C-terminus as a nuclear export signal (NES) of class A Hsfs. Sequence comparison indicates that the combination of a C-terminal AHA motif with the consensus sequence FWxxF/L,F/I/L as well as the adjacent NES represents a signature domain for plant class A Hsfs, which allowed to identify more than 60 new Hsfs from the expressed sequence tag (EST) database.

Kotak S, Port M, Ganguli A, Bicker F, von Koskull-Doring P.
Characterization of C-terminal domains of Arabidopsis heat stress transcription factors (Hsfs) and identification of a new signature combination of plant class A Hsfs with AHA and NES motifs essential for activator function and intracellular localization.
Plant J, 2004. 39(1): p. 98-112.
PMID: 15200645