PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Oropetium thomaeum
ARF Family
Species TF ID Description
Oropetium_20150105_02810AARF family protein
Oropetium_20150105_11651AARF family protein
Oropetium_20150105_12124AARF family protein
Oropetium_20150105_12537AARF family protein
Oropetium_20150105_14416AARF family protein
Oropetium_20150105_14774AARF family protein
Oropetium_20150105_15589AARF family protein
Oropetium_20150105_16186AARF family protein
Oropetium_20150105_16300AARF family protein
Oropetium_20150105_17235AARF family protein
Oropetium_20150105_18237AARF family protein
Oropetium_20150105_19850AARF family protein
Oropetium_20150105_24908AARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969