PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza sativa subsp. indica
GRF Family
Species TF ID Description
BGIOSGA005497-PAGRF family protein
BGIOSGA005785-PAGRF family protein
BGIOSGA008811-PAGRF family protein
BGIOSGA013306-PAGRF family protein
BGIOSGA013307-PAGRF family protein
BGIOSGA013499-PAGRF family protein
BGIOSGA014417-PAGRF family protein
BGIOSGA016961-PAGRF family protein
BGIOSGA022056-PAGRF family protein
BGIOSGA022506-PAGRF family protein
BGIOSGA025662-PAGRF family protein
BGIOSGA035433-PAGRF family protein
BGIOSGA037400-PAGRF family protein
GRF Family Introduction

Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Kim JH, Choi D, Kende H.
The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis.
Plant J. 2003 Oct;36(1):94-104.
PMID: 12974814