PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza sativa subsp. indica
FAR1 Family
Species TF ID Description
BGIOSGA003621-PAFAR1 family protein
BGIOSGA006277-PAFAR1 family protein
BGIOSGA006294-PAFAR1 family protein
BGIOSGA006918-PAFAR1 family protein
BGIOSGA007279-PAFAR1 family protein
BGIOSGA007977-PAFAR1 family protein
BGIOSGA008313-PAFAR1 family protein
BGIOSGA008594-PAFAR1 family protein
BGIOSGA008595-PAFAR1 family protein
BGIOSGA009723-PAFAR1 family protein
BGIOSGA009913-PAFAR1 family protein
BGIOSGA010323-PAFAR1 family protein
BGIOSGA010384-PAFAR1 family protein
BGIOSGA011396-PAFAR1 family protein
BGIOSGA011986-PAFAR1 family protein
BGIOSGA012253-PAFAR1 family protein
BGIOSGA012540-PAFAR1 family protein
BGIOSGA013920-PAFAR1 family protein
BGIOSGA014351-PAFAR1 family protein
BGIOSGA015115-PAFAR1 family protein
BGIOSGA015399-PAFAR1 family protein
BGIOSGA016307-PAFAR1 family protein
BGIOSGA016602-PAFAR1 family protein
BGIOSGA016802-PAFAR1 family protein
BGIOSGA018311-PAFAR1 family protein
BGIOSGA019718-PAFAR1 family protein
BGIOSGA019720-PAFAR1 family protein
BGIOSGA020556-PAFAR1 family protein
BGIOSGA020952-PAFAR1 family protein
BGIOSGA021243-PAFAR1 family protein
BGIOSGA021543-PAFAR1 family protein
BGIOSGA022378-PAFAR1 family protein
BGIOSGA022621-PAFAR1 family protein
BGIOSGA022694-PAFAR1 family protein
BGIOSGA022779-PAFAR1 family protein
BGIOSGA022898-PAFAR1 family protein
BGIOSGA022910-PAFAR1 family protein
BGIOSGA023036-PAFAR1 family protein
BGIOSGA023199-PAFAR1 family protein
BGIOSGA024182-PAFAR1 family protein
BGIOSGA024272-PAFAR1 family protein
BGIOSGA025537-PAFAR1 family protein
BGIOSGA025647-PAFAR1 family protein
BGIOSGA025749-PAFAR1 family protein
BGIOSGA025948-PAFAR1 family protein
BGIOSGA026135-PAFAR1 family protein
BGIOSGA026335-PAFAR1 family protein
BGIOSGA028053-PAFAR1 family protein
BGIOSGA028546-PAFAR1 family protein
BGIOSGA028683-PAFAR1 family protein
BGIOSGA030038-PAFAR1 family protein
BGIOSGA030369-PAFAR1 family protein
BGIOSGA031362-PAFAR1 family protein
BGIOSGA032120-PAFAR1 family protein
BGIOSGA032671-PAFAR1 family protein
BGIOSGA033234-PAFAR1 family protein
BGIOSGA034052-PAFAR1 family protein
BGIOSGA034216-PAFAR1 family protein
BGIOSGA035149-PAFAR1 family protein
BGIOSGA035151-PAFAR1 family protein
BGIOSGA036435-PAFAR1 family protein
BGIOSGA036688-PAFAR1 family protein
BGIOSGA037017-PAFAR1 family protein
BGIOSGA037035-PAFAR1 family protein
BGIOSGA037850-PAFAR1 family protein
BGIOSGA037985-PAFAR1 family protein
BGIOSGA038072-PAFAR1 family protein
BGIOSGA038559-PAFAR1 family protein
BGIOSGA040495-PAFAR1 family protein
BGIOSGA040624-PAFAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885