PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza rufipogon
bHLH Family
Species TF ID Description
ORUFI01G00370.1bHLH family protein
ORUFI01G00600.1bHLH family protein
ORUFI01G00830.1bHLH family protein
ORUFI01G04050.1bHLH family protein
ORUFI01G06700.1bHLH family protein
ORUFI01G06710.1bHLH family protein
ORUFI01G08040.1bHLH family protein
ORUFI01G09400.1bHLH family protein
ORUFI01G12840.1bHLH family protein
ORUFI01G13250.1bHLH family protein
ORUFI01G19830.1bHLH family protein
ORUFI01G22390.1bHLH family protein
ORUFI01G22920.1bHLH family protein
ORUFI01G22990.1bHLH family protein
ORUFI01G23050.1bHLH family protein
ORUFI01G31210.1bHLH family protein
ORUFI01G31350.1bHLH family protein
ORUFI01G35930.1bHLH family protein
ORUFI01G36520.1bHLH family protein
ORUFI01G39410.1bHLH family protein
ORUFI01G41760.1bHLH family protein
ORUFI01G41760.2bHLH family protein
ORUFI01G44010.1bHLH family protein
ORUFI01G45060.1bHLH family protein
ORUFI01G46010.1bHLH family protein
ORUFI01G47560.1bHLH family protein
ORUFI02G01220.1bHLH family protein
ORUFI02G01530.1bHLH family protein
ORUFI02G09060.1bHLH family protein
ORUFI02G09720.1bHLH family protein
ORUFI02G11080.1bHLH family protein
ORUFI02G21070.1bHLH family protein
ORUFI02G21080.1bHLH family protein
ORUFI02G21960.1bHLH family protein
ORUFI02G24640.1bHLH family protein
ORUFI02G30170.1bHLH family protein
ORUFI02G31120.1bHLH family protein
ORUFI02G31420.1bHLH family protein
ORUFI02G32620.1bHLH family protein
ORUFI02G34170.1bHLH family protein
ORUFI02G34810.1bHLH family protein
ORUFI02G37320.1bHLH family protein
ORUFI02G37320.3bHLH family protein
ORUFI02G37990.1bHLH family protein
ORUFI03G01470.1bHLH family protein
ORUFI03G02540.1bHLH family protein
ORUFI03G05130.4bHLH family protein
ORUFI03G05150.1bHLH family protein
ORUFI03G06370.1bHLH family protein
ORUFI03G07580.1bHLH family protein
ORUFI03G09460.1bHLH family protein
ORUFI03G09600.1bHLH family protein
ORUFI03G09600.2bHLH family protein
ORUFI03G11650.1bHLH family protein
ORUFI03G13300.1bHLH family protein
ORUFI03G20000.1bHLH family protein
ORUFI03G20760.1bHLH family protein
ORUFI03G27070.1bHLH family protein
ORUFI03G28150.1bHLH family protein
ORUFI03G30180.1bHLH family protein
ORUFI03G30210.1bHLH family protein
ORUFI03G33950.1bHLH family protein
ORUFI03G33950.2bHLH family protein
ORUFI03G34210.1bHLH family protein
ORUFI03G34980.5bHLH family protein
ORUFI03G36360.1bHLH family protein
ORUFI03G36360.2bHLH family protein
ORUFI03G36640.1bHLH family protein
ORUFI03G37840.1bHLH family protein
ORUFI03G37840.2bHLH family protein
ORUFI03G37840.3bHLH family protein
ORUFI03G37840.4bHLH family protein
ORUFI03G37840.5bHLH family protein
ORUFI03G37840.6bHLH family protein
ORUFI03G37840.7bHLH family protein
ORUFI03G37840.8bHLH family protein
ORUFI03G39460.1bHLH family protein
ORUFI03G40090.1bHLH family protein
ORUFI04G07840.1bHLH family protein
ORUFI04G07840.2bHLH family protein
ORUFI04G07860.1bHLH family protein
ORUFI04G09760.1bHLH family protein
ORUFI04G11150.1bHLH family protein
ORUFI04G14020.1bHLH family protein
ORUFI04G18350.1bHLH family protein
ORUFI04G18350.2bHLH family protein
ORUFI04G22890.1bHLH family protein
ORUFI04G22910.1bHLH family protein
ORUFI04G22910.2bHLH family protein
ORUFI04G22910.3bHLH family protein
ORUFI04G25160.1bHLH family protein
ORUFI04G25690.1bHLH family protein
ORUFI04G27110.1bHLH family protein
ORUFI04G28640.1bHLH family protein
ORUFI05G00210.1bHLH family protein
ORUFI05G02750.1bHLH family protein
ORUFI05G04170.1bHLH family protein
ORUFI05G04670.1bHLH family protein
ORUFI05G04670.2bHLH family protein
ORUFI05G06870.1bHLH family protein
ORUFI05G23130.1bHLH family protein
ORUFI05G25940.1bHLH family protein
ORUFI05G29450.1bHLH family protein
ORUFI05G30290.1bHLH family protein
ORUFI06G04330.1bHLH family protein
ORUFI06G05560.1bHLH family protein
ORUFI06G06220.1bHLH family protein
ORUFI06G06220.2bHLH family protein
ORUFI06G06220.3bHLH family protein
ORUFI06G07280.1bHLH family protein
ORUFI06G11220.1bHLH family protein
ORUFI06G17910.1bHLH family protein
ORUFI06G19010.1bHLH family protein
ORUFI06G20120.1bHLH family protein
ORUFI06G22420.1bHLH family protein
ORUFI06G29810.1bHLH family protein
ORUFI07G02530.1bHLH family protein
ORUFI07G02530.2bHLH family protein
ORUFI07G05060.1bHLH family protein
ORUFI07G06050.1bHLH family protein
ORUFI07G07120.1bHLH family protein
ORUFI07G18300.1bHLH family protein
ORUFI07G18300.2bHLH family protein
ORUFI07G18720.1bHLH family protein
ORUFI07G21430.1bHLH family protein
ORUFI07G24160.1bHLH family protein
ORUFI08G00650.1bHLH family protein
ORUFI08G02650.1bHLH family protein
ORUFI08G05340.1bHLH family protein
ORUFI08G05340.2bHLH family protein
ORUFI08G17560.1bHLH family protein
ORUFI08G19930.1bHLH family protein
ORUFI08G20260.1bHLH family protein
ORUFI08G20670.1bHLH family protein
ORUFI08G20920.1bHLH family protein
ORUFI08G21030.1bHLH family protein
ORUFI08G22260.1bHLH family protein
ORUFI08G23530.1bHLH family protein
ORUFI08G24310.1bHLH family protein
ORUFI08G24840.1bHLH family protein
ORUFI09G10670.1bHLH family protein
ORUFI09G11120.1bHLH family protein
ORUFI09G13650.1bHLH family protein
ORUFI09G14130.1bHLH family protein
ORUFI09G14410.1bHLH family protein
ORUFI09G14750.1bHLH family protein
ORUFI09G14830.1bHLH family protein
ORUFI09G15820.1bHLH family protein
ORUFI09G16640.1bHLH family protein
ORUFI09G17270.1bHLH family protein
ORUFI09G17270.2bHLH family protein
ORUFI09G17940.1bHLH family protein
ORUFI10G08570.1bHLH family protein
ORUFI10G09690.1bHLH family protein
ORUFI10G09730.1bHLH family protein
ORUFI10G18500.1bHLH family protein
ORUFI10G19390.1bHLH family protein
ORUFI10G19390.2bHLH family protein
ORUFI10G19390.3bHLH family protein
ORUFI10G20700.1bHLH family protein
ORUFI11G03710.1bHLH family protein
ORUFI11G09150.1bHLH family protein
ORUFI11G12850.1bHLH family protein
ORUFI11G16280.1bHLH family protein
ORUFI11G20520.1bHLH family protein
ORUFI11G22390.1bHLH family protein
ORUFI12G13970.1bHLH family protein
ORUFI12G14590.1bHLH family protein
ORUFI12G19280.1bHLH family protein
ORUFI12G19830.1bHLH family protein
ORUFI12G19840.1bHLH family protein
ORUFI12G19860.1bHLH family protein
ORUFI12G19880.1bHLH family protein
ORUFI12G19910.1bHLH family protein
ORUFI12G20600.1bHLH family protein
ORUFI12G22050.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250