PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza rufipogon
HD-ZIP Family
Species TF ID Description
ORUFI08G20510.1HD-ZIP family protein
ORUFI02G32840.1HD-ZIP family protein
ORUFI02G32840.2HD-ZIP family protein
ORUFI09G14530.1HD-ZIP family protein
ORUFI08G16530.1HD-ZIP family protein
ORUFI03G05090.1HD-ZIP family protein
ORUFI04G22350.1HD-ZIP family protein
ORUFI08G19510.1HD-ZIP family protein
ORUFI03G06390.1HD-ZIP family protein
ORUFI10G09770.1HD-ZIP family protein
ORUFI09G13050.1HD-ZIP family protein
ORUFI10G00170.1HD-ZIP family protein
ORUFI02G22050.1HD-ZIP family protein
ORUFI04G21910.1HD-ZIP family protein
ORUFI06G02550.1HD-ZIP family protein
ORUFI03G09550.1HD-ZIP family protein
ORUFI06G02570.1HD-ZIP family protein
ORUFI02G27420.1HD-ZIP family protein
ORUFI09G09080.1HD-ZIP family protein
ORUFI01G27220.1HD-ZIP family protein
ORUFI06G28040.1HD-ZIP family protein
ORUFI07G20840.1HD-ZIP family protein
ORUFI02G03950.1HD-ZIP family protein
ORUFI03G07070.1HD-ZIP family protein
ORUFI01G45310.1HD-ZIP family protein
ORUFI08G05670.1HD-ZIP family protein
ORUFI04G27800.1HD-ZIP family protein
ORUFI08G02510.1HD-ZIP family protein
ORUFI02G29080.1HD-ZIP family protein
ORUFI09G18410.1HD-ZIP family protein
ORUFI01G34950.1HD-ZIP family protein
ORUFI03G28280.1HD-ZIP family protein
ORUFI12G20830.2HD-ZIP family protein
ORUFI12G20830.1HD-ZIP family protein
ORUFI03G00510.2HD-ZIP family protein
ORUFI03G00510.3HD-ZIP family protein
ORUFI03G00510.1HD-ZIP family protein
ORUFI03G00510.4HD-ZIP family protein
ORUFI04G23720.2HD-ZIP family protein
ORUFI04G23720.1HD-ZIP family protein
ORUFI10G14170.1HD-ZIP family protein
ORUFI10G14170.2HD-ZIP family protein
ORUFI06G07070.2HD-ZIP family protein
ORUFI01G06940.4HD-ZIP family protein
ORUFI01G06940.3HD-ZIP family protein
ORUFI06G07070.1HD-ZIP family protein
ORUFI01G06940.1HD-ZIP family protein
ORUFI01G06940.2HD-ZIP family protein
ORUFI10G20730.1HD-ZIP family protein
ORUFI08G10670.1HD-ZIP family protein
ORUFI01G36780.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401