PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Oryza rufipogon
BES1 Family
Species TF ID Description
ORUFI01G05260.1BES1 family protein
ORUFI01G07130.1BES1 family protein
ORUFI01G07130.2BES1 family protein
ORUFI02G02360.1BES1 family protein
ORUFI02G02360.2BES1 family protein
ORUFI02G02360.3BES1 family protein
ORUFI02G09890.1BES1 family protein
ORUFI06G19240.1BES1 family protein
ORUFI07G20760.1BES1 family protein
ORUFI09G21750.1BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330