PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Ostreococcus sp. RCC809
MYB Family
Species TF ID Description
e_gw1.13.188.1MYB family protein
e_gw1.5.110.1MYB family protein
e_gw1.5.42.1MYB family protein
e_gw1.9.523.1MYB family protein
e_gw1.9.712.1MYB family protein
fgenesh1_pg.chr_14_#_72MYB family protein
gw1.11.979.1MYB family protein
gw1.14.195.1MYB family protein
gw1.14.729.1MYB family protein
gw1.17.616.1MYB family protein
gw1.5.1139.1MYB family protein
MYB Family Introduction

MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the "oncogene" v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.

In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as "MYB1R factors", with two as "R2R3-type MYB" factors, and with three repeats as "MYB3R" factors.

Stracke R, Werber M, Weisshaar B.
The R2R3-MYB gene family in Arabidopsis thaliana.
Curr Opin Plant Biol. 2001 Oct;4(5):447-56. Review.
PMID: 11597504