PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza punctata
HD-ZIP Family
Species TF ID Description
OPUNC02G19040.1HD-ZIP family protein
OPUNC08G16250.1HD-ZIP family protein
OPUNC02G28870.1HD-ZIP family protein
OPUNC08G13170.1HD-ZIP family protein
OPUNC09G11870.1HD-ZIP family protein
OPUNC03G05000.1HD-ZIP family protein
OPUNC04G18440.1HD-ZIP family protein
OPUNC08G15320.1HD-ZIP family protein
OPUNC10G08110.1HD-ZIP family protein
OPUNC09G10660.1HD-ZIP family protein
OPUNC03G06250.1HD-ZIP family protein
OPUNC10G16910.1HD-ZIP family protein
OPUNC02G19040.2HD-ZIP family protein
OPUNC04G17950.1HD-ZIP family protein
OPUNC03G09020.1HD-ZIP family protein
OPUNC10G07080.1HD-ZIP family protein
OPUNC10G00220.1HD-ZIP family protein
OPUNC06G02410.1HD-ZIP family protein
OPUNC06G02400.1HD-ZIP family protein
OPUNC02G23740.1HD-ZIP family protein
OPUNC09G07160.1HD-ZIP family protein
OPUNC01G24390.1HD-ZIP family protein
OPUNC09G15600.1HD-ZIP family protein
OPUNC06G23700.1HD-ZIP family protein
OPUNC07G18930.1HD-ZIP family protein
OPUNC03G06940.1HD-ZIP family protein
OPUNC02G03070.1HD-ZIP family protein
OPUNC09G10660.3HD-ZIP family protein
OPUNC09G10660.2HD-ZIP family protein
OPUNC11G16030.1HD-ZIP family protein
OPUNC05G24410.1HD-ZIP family protein
OPUNC08G04870.1HD-ZIP family protein
OPUNC04G23630.1HD-ZIP family protein
OPUNC08G02090.1HD-ZIP family protein
OPUNC02G25360.1HD-ZIP family protein
OPUNC09G15430.1HD-ZIP family protein
OPUNC01G30780.1HD-ZIP family protein
OPUNC03G24840.1HD-ZIP family protein
OPUNC12G16840.1HD-ZIP family protein
OPUNC03G00630.1HD-ZIP family protein
OPUNC03G00630.2HD-ZIP family protein
OPUNC03G00670.1HD-ZIP family protein
OPUNC03G00670.2HD-ZIP family protein
OPUNC10G11850.1HD-ZIP family protein
OPUNC06G06470.1HD-ZIP family protein
OPUNC01G06180.1HD-ZIP family protein
OPUNC10G17890.1HD-ZIP family protein
OPUNC10G17920.1HD-ZIP family protein
OPUNC08G08700.1HD-ZIP family protein
OPUNC04G19830.1HD-ZIP family protein
OPUNC01G32670.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401