PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza nivara
HD-ZIP Family
Species TF ID Description
ONIVA08G20420.1HD-ZIP family protein
ONIVA02G34350.1HD-ZIP family protein
ONIVA09G13990.1HD-ZIP family protein
ONIVA08G15620.1HD-ZIP family protein
ONIVA04G19000.1HD-ZIP family protein
ONIVA03G05120.1HD-ZIP family protein
ONIVA02G06360.1HD-ZIP family protein
ONIVA03G20220.1HD-ZIP family protein
ONIVA09G13320.1HD-ZIP family protein
ONIVA02G23130.1HD-ZIP family protein
ONIVA10G07840.1HD-ZIP family protein
ONIVA10G00410.1HD-ZIP family protein
ONIVA04G18550.1HD-ZIP family protein
ONIVA02G39180.1HD-ZIP family protein
ONIVA06G03230.1HD-ZIP family protein
ONIVA06G03250.1HD-ZIP family protein
ONIVA02G28400.1HD-ZIP family protein
ONIVA12G12160.1HD-ZIP family protein
ONIVA01G27550.1HD-ZIP family protein
ONIVA06G28660.1HD-ZIP family protein
ONIVA07G18470.1HD-ZIP family protein
ONIVA05G18090.1HD-ZIP family protein
ONIVA03G06860.1HD-ZIP family protein
ONIVA05G28880.1HD-ZIP family protein
ONIVA08G05020.1HD-ZIP family protein
ONIVA04G25060.1HD-ZIP family protein
ONIVA08G02450.1HD-ZIP family protein
ONIVA02G30520.1HD-ZIP family protein
ONIVA09G18120.1HD-ZIP family protein
ONIVA01G36080.1HD-ZIP family protein
ONIVA03G28370.1HD-ZIP family protein
ONIVA12G17580.2HD-ZIP family protein
ONIVA12G17580.1HD-ZIP family protein
ONIVA11G21180.2HD-ZIP family protein
ONIVA11G21180.3HD-ZIP family protein
ONIVA11G21180.1HD-ZIP family protein
ONIVA04G20660.1HD-ZIP family protein
ONIVA01G07970.6HD-ZIP family protein
ONIVA01G07970.5HD-ZIP family protein
ONIVA01G07970.4HD-ZIP family protein
ONIVA10G14800.1HD-ZIP family protein
ONIVA10G14800.2HD-ZIP family protein
ONIVA01G07970.2HD-ZIP family protein
ONIVA01G07970.3HD-ZIP family protein
ONIVA06G08130.1HD-ZIP family protein
ONIVA01G07970.1HD-ZIP family protein
ONIVA10G22060.1HD-ZIP family protein
ONIVA01G38360.1HD-ZIP family protein
ONIVA10G10170.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401