PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza meridionalis
HD-ZIP Family
Species TF ID Description
OMERI08G14350.1HD-ZIP family protein
OMERI07G06640.1HD-ZIP family protein
OMERI02G30000.1HD-ZIP family protein
OMERI03G04970.1HD-ZIP family protein
OMERI04G17200.2HD-ZIP family protein
OMERI04G17200.1HD-ZIP family protein
OMERI08G14040.2HD-ZIP family protein
OMERI10G06620.1HD-ZIP family protein
OMERI03G06380.1HD-ZIP family protein
OMERI09G09650.1HD-ZIP family protein
OMERI08G00390.1HD-ZIP family protein
OMERI02G20780.3HD-ZIP family protein
OMERI02G20780.1HD-ZIP family protein
OMERI06G02490.1HD-ZIP family protein
OMERI02G20780.2HD-ZIP family protein
OMERI06G02830.1HD-ZIP family protein
OMERI09G12780.1HD-ZIP family protein
OMERI02G25450.1HD-ZIP family protein
OMERI01G22370.1HD-ZIP family protein
OMERI09G06770.1HD-ZIP family protein
OMERI07G16720.1HD-ZIP family protein
OMERI06G26300.1HD-ZIP family protein
OMERI02G04720.1HD-ZIP family protein
OMERI03G06990.1HD-ZIP family protein
OMERI08G14040.1HD-ZIP family protein
OMERI08G02310.1HD-ZIP family protein
OMERI02G26880.1HD-ZIP family protein
OMERI09G12650.1HD-ZIP family protein
OMERI03G00550.1HD-ZIP family protein
OMERI03G00550.2HD-ZIP family protein
OMERI01G28810.1HD-ZIP family protein
OMERI03G00480.2HD-ZIP family protein
OMERI03G00480.1HD-ZIP family protein
OMERI04G18610.2HD-ZIP family protein
OMERI04G18610.1HD-ZIP family protein
OMERI10G10230.4HD-ZIP family protein
OMERI10G10230.1HD-ZIP family protein
OMERI10G10230.2HD-ZIP family protein
OMERI10G10230.5HD-ZIP family protein
OMERI01G06500.2HD-ZIP family protein
OMERI06G08000.1HD-ZIP family protein
OMERI01G06500.1HD-ZIP family protein
OMERI01G06500.3HD-ZIP family protein
OMERI10G10230.3HD-ZIP family protein
OMERI10G15290.1HD-ZIP family protein
OMERI12G14040.1HD-ZIP family protein
OMERI08G08060.4HD-ZIP family protein
OMERI08G08060.1HD-ZIP family protein
OMERI08G08060.3HD-ZIP family protein
OMERI08G08060.2HD-ZIP family protein
OMERI01G30450.1HD-ZIP family protein
OMERI08G08060.5HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401