PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza longistaminata
bHLH Family
Species TF ID Description
AMDW01019491.1_FGP001bHLH family protein
AMDW01021712.1_FGP001bHLH family protein
AMDW01031827.1_FGP001bHLH family protein
AMDW01036740.1_FGP001bHLH family protein
AMDW01136750.1_FGP001bHLH family protein
KN538682.1_FGP028bHLH family protein
KN538684.1_FGP020bHLH family protein
KN538684.1_FGP054bHLH family protein
KN538687.1_FGP060bHLH family protein
KN538688.1_FGP001bHLH family protein
KN538703.1_FGP010bHLH family protein
KN538718.1_FGP059bHLH family protein
KN538719.1_FGP045bHLH family protein
KN538723.1_FGP011bHLH family protein
KN538727.1_FGP013bHLH family protein
KN538728.1_FGP070bHLH family protein
KN538733.1_FGP096bHLH family protein
KN538737.1_FGP012bHLH family protein
KN538746.1_FGP031bHLH family protein
KN538748.1_FGP005bHLH family protein
KN538748.1_FGP013bHLH family protein
KN538752.1_FGP072bHLH family protein
KN538762.1_FGP010bHLH family protein
KN538784.1_FGP006bHLH family protein
KN538809.1_FGP036bHLH family protein
KN538818.1_FGP009bHLH family protein
KN538826.1_FGP062bHLH family protein
KN538831.1_FGP016bHLH family protein
KN538831.1_FGP018bHLH family protein
KN538834.1_FGP009bHLH family protein
KN538836.1_FGP007bHLH family protein
KN538838.1_FGP021bHLH family protein
KN538842.1_FGP025bHLH family protein
KN538856.1_FGP004bHLH family protein
KN538860.1_FGP008bHLH family protein
KN538861.1_FGP007bHLH family protein
KN538867.1_FGP022bHLH family protein
KN538873.1_FGP012bHLH family protein
KN538875.1_FGP037bHLH family protein
KN538886.1_FGP018bHLH family protein
KN538902.1_FGP025bHLH family protein
KN538904.1_FGP001bHLH family protein
KN538907.1_FGP001bHLH family protein
KN538909.1_FGP014bHLH family protein
KN538920.1_FGP018bHLH family protein
KN538928.1_FGP024bHLH family protein
KN538953.1_FGP004bHLH family protein
KN538954.1_FGP008bHLH family protein
KN538958.1_FGP004bHLH family protein
KN538958.1_FGP007bHLH family protein
KN538977.1_FGP006bHLH family protein
KN538977.1_FGP017bHLH family protein
KN538977.1_FGP021bHLH family protein
KN538978.1_FGP010bHLH family protein
KN538988.1_FGP001bHLH family protein
KN539001.1_FGP011bHLH family protein
KN539047.1_FGP010bHLH family protein
KN539052.1_FGP012bHLH family protein
KN539060.1_FGP003bHLH family protein
KN539102.1_FGP001bHLH family protein
KN539176.1_FGP009bHLH family protein
KN539183.1_FGP017bHLH family protein
KN539184.1_FGP005bHLH family protein
KN539185.1_FGP003bHLH family protein
KN539201.1_FGP004bHLH family protein
KN539216.1_FGP012bHLH family protein
KN539226.1_FGP001bHLH family protein
KN539249.1_FGP013bHLH family protein
KN539305.1_FGP003bHLH family protein
KN539305.1_FGP004bHLH family protein
KN539331.1_FGP002bHLH family protein
KN539340.1_FGP011bHLH family protein
KN539351.1_FGP002bHLH family protein
KN539356.1_FGP011bHLH family protein
KN539428.1_FGP004bHLH family protein
KN539428.1_FGP006bHLH family protein
KN539451.1_FGP011bHLH family protein
KN539452.1_FGP006bHLH family protein
KN539457.1_FGP004bHLH family protein
KN539536.1_FGP004bHLH family protein
KN539550.1_FGP001bHLH family protein
KN539577.1_FGP002bHLH family protein
KN539600.1_FGP005bHLH family protein
KN539640.1_FGP004bHLH family protein
KN539729.1_FGP002bHLH family protein
KN539761.1_FGP002bHLH family protein
KN539819.1_FGP007bHLH family protein
KN539861.1_FGP001bHLH family protein
KN539878.1_FGP008bHLH family protein
KN539960.1_FGP002bHLH family protein
KN540005.1_FGP002bHLH family protein
KN540018.1_FGP007bHLH family protein
KN540043.1_FGP007bHLH family protein
KN540074.1_FGP007bHLH family protein
KN540075.1_FGP002bHLH family protein
KN540122.1_FGP005bHLH family protein
KN540132.1_FGP004bHLH family protein
KN540163.1_FGP007bHLH family protein
KN540200.1_FGP002bHLH family protein
KN540220.1_FGP002bHLH family protein
KN540256.1_FGP008bHLH family protein
KN540276.1_FGP003bHLH family protein
KN540336.1_FGP006bHLH family protein
KN540355.1_FGP002bHLH family protein
KN540360.1_FGP005bHLH family protein
KN540698.1_FGP001bHLH family protein
KN540737.1_FGP001bHLH family protein
KN540745.1_FGP001bHLH family protein
KN540892.1_FGP002bHLH family protein
KN541242.1_FGP002bHLH family protein
KN541742.1_FGP001bHLH family protein
KN541806.1_FGP002bHLH family protein
KN541807.1_FGP002bHLH family protein
KN541998.1_FGP001bHLH family protein
KN543701.1_FGP001bHLH family protein
KN545330.1_FGP001bHLH family protein
KN546796.1_FGP001bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250