PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza glumaepatula
HD-ZIP Family
Species TF ID Description
OGLUM08G19260.1HD-ZIP family protein
OGLUM02G31840.1HD-ZIP family protein
OGLUM02G31840.2HD-ZIP family protein
OGLUM09G14010.1HD-ZIP family protein
OGLUM08G15410.1HD-ZIP family protein
OGLUM03G05180.1HD-ZIP family protein
OGLUM04G20690.1HD-ZIP family protein
OGLUM08G18270.1HD-ZIP family protein
OGLUM10G09180.1HD-ZIP family protein
OGLUM10G09180.2HD-ZIP family protein
OGLUM03G06560.1HD-ZIP family protein
OGLUM03G06560.2HD-ZIP family protein
OGLUM09G12570.1HD-ZIP family protein
OGLUM02G21270.3HD-ZIP family protein
OGLUM02G21270.4HD-ZIP family protein
OGLUM10G18660.1HD-ZIP family protein
OGLUM10G00200.1HD-ZIP family protein
OGLUM02G21270.1HD-ZIP family protein
OGLUM10G07890.1HD-ZIP family protein
OGLUM04G20240.1HD-ZIP family protein
OGLUM06G02590.1HD-ZIP family protein
OGLUM03G09500.1HD-ZIP family protein
OGLUM06G02610.1HD-ZIP family protein
OGLUM02G26440.1HD-ZIP family protein
OGLUM09G08880.1HD-ZIP family protein
OGLUM01G28210.1HD-ZIP family protein
OGLUM06G27470.1HD-ZIP family protein
OGLUM07G19800.1HD-ZIP family protein
OGLUM02G03650.1HD-ZIP family protein
OGLUM03G07230.1HD-ZIP family protein
OGLUM01G46130.1HD-ZIP family protein
OGLUM08G05340.1HD-ZIP family protein
OGLUM08G02240.1HD-ZIP family protein
OGLUM04G26010.2HD-ZIP family protein
OGLUM04G26010.1HD-ZIP family protein
OGLUM02G28170.1HD-ZIP family protein
OGLUM09G17630.1HD-ZIP family protein
OGLUM03G27880.2HD-ZIP family protein
OGLUM03G27880.1HD-ZIP family protein
OGLUM01G35890.1HD-ZIP family protein
OGLUM12G20280.2HD-ZIP family protein
OGLUM12G20280.1HD-ZIP family protein
OGLUM03G00670.2HD-ZIP family protein
OGLUM03G00670.1HD-ZIP family protein
OGLUM01G07380.3HD-ZIP family protein
OGLUM10G13240.1HD-ZIP family protein
OGLUM10G13240.2HD-ZIP family protein
OGLUM01G07380.1HD-ZIP family protein
OGLUM06G07200.1HD-ZIP family protein
OGLUM04G22100.1HD-ZIP family protein
OGLUM10G19540.1HD-ZIP family protein
OGLUM01G07380.2HD-ZIP family protein
OGLUM08G10180.2HD-ZIP family protein
OGLUM08G10180.3HD-ZIP family protein
OGLUM08G10180.1HD-ZIP family protein
OGLUM01G37810.1HD-ZIP family protein
OGLUM08G10180.4HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401