PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza glaberrima
bHLH Family
Species TF ID Description
ORGLA01G0003200.1bHLH family protein
ORGLA01G0005100.1bHLH family protein
ORGLA01G0005200.1bHLH family protein
ORGLA01G0007400.1bHLH family protein
ORGLA01G0034700.1bHLH family protein
ORGLA01G0058200.1bHLH family protein
ORGLA01G0065100.1bHLH family protein
ORGLA01G0077100.1bHLH family protein
ORGLA01G0103700.1bHLH family protein
ORGLA01G0146100.1bHLH family protein
ORGLA01G0163600.1bHLH family protein
ORGLA01G0232100.1bHLH family protein
ORGLA01G0233600.1bHLH family protein
ORGLA01G0267200.1bHLH family protein
ORGLA01G0299600.1bHLH family protein
ORGLA01G0322000.1bHLH family protein
ORGLA01G0346300.1bHLH family protein
ORGLA01G0356500.1bHLH family protein
ORGLA01G0363500.1bHLH family protein
ORGLA01G0380200.1bHLH family protein
ORGLA01G0397100.1bHLH family protein
ORGLA02G0011200.1bHLH family protein
ORGLA02G0014200.1bHLH family protein
ORGLA02G0086900.1bHLH family protein
ORGLA02G0100500.1bHLH family protein
ORGLA02G0170900.1bHLH family protein
ORGLA02G0180000.1bHLH family protein
ORGLA02G0200100.1bHLH family protein
ORGLA02G0246400.1bHLH family protein
ORGLA02G0252900.1bHLH family protein
ORGLA02G0253300.1bHLH family protein
ORGLA02G0264700.1bHLH family protein
ORGLA02G0280200.1bHLH family protein
ORGLA02G0287300.1bHLH family protein
ORGLA02G0311000.1bHLH family protein
ORGLA02G0316800.1bHLH family protein
ORGLA02G0343900.1bHLH family protein
ORGLA03G0015000.1bHLH family protein
ORGLA03G0026100.1bHLH family protein
ORGLA03G0051100.1bHLH family protein
ORGLA03G0051300.1bHLH family protein
ORGLA03G0062600.1bHLH family protein
ORGLA03G0073500.1bHLH family protein
ORGLA03G0090200.1bHLH family protein
ORGLA03G0109100.1bHLH family protein
ORGLA03G0122000.1bHLH family protein
ORGLA03G0182200.1bHLH family protein
ORGLA03G0187700.1bHLH family protein
ORGLA03G0242600.1bHLH family protein
ORGLA03G0268800.1bHLH family protein
ORGLA03G0269200.1bHLH family protein
ORGLA03G0295100.1bHLH family protein
ORGLA03G0297500.1bHLH family protein
ORGLA03G0304100.1bHLH family protein
ORGLA03G0319700.1bHLH family protein
ORGLA03G0322200.1bHLH family protein
ORGLA03G0333400.1bHLH family protein
ORGLA03G0340500.1bHLH family protein
ORGLA03G0344800.1bHLH family protein
ORGLA03G0352000.1bHLH family protein
ORGLA04G0051300.1bHLH family protein
ORGLA04G0072000.1bHLH family protein
ORGLA04G0098400.1bHLH family protein
ORGLA04G0098500.1bHLH family protein
ORGLA04G0140000.1bHLH family protein
ORGLA04G0183800.1bHLH family protein
ORGLA04G0183900.1bHLH family protein
ORGLA04G0184100.1bHLH family protein
ORGLA04G0200200.1bHLH family protein
ORGLA04G0205200.1bHLH family protein
ORGLA04G0213700.1bHLH family protein
ORGLA04G0225800.1bHLH family protein
ORGLA04G0234000.1bHLH family protein
ORGLA05G0001800.1bHLH family protein
ORGLA05G0025000.1bHLH family protein
ORGLA05G0037900.1bHLH family protein
ORGLA05G0041400.1bHLH family protein
ORGLA05G0058200.1bHLH family protein
ORGLA05G0163800.1bHLH family protein
ORGLA05G0190400.1bHLH family protein
ORGLA05G0208300.1bHLH family protein
ORGLA05G0238800.1bHLH family protein
ORGLA05G0246000.1bHLH family protein
ORGLA06G0039900.1bHLH family protein
ORGLA06G0049400.1bHLH family protein
ORGLA06G0065500.1bHLH family protein
ORGLA06G0076300.1bHLH family protein
ORGLA06G0099500.1bHLH family protein
ORGLA06G0131200.1bHLH family protein
ORGLA06G0140300.1bHLH family protein
ORGLA06G0157800.1bHLH family protein
ORGLA06G0235300.1bHLH family protein
ORGLA06G0244900.1bHLH family protein
ORGLA06G0253200.1bHLH family protein
ORGLA06G0286200.1bHLH family protein
ORGLA06G0299700.1bHLH family protein
ORGLA07G0023700.1bHLH family protein
ORGLA07G0044500.1bHLH family protein
ORGLA07G0051400.1bHLH family protein
ORGLA07G0141300.1bHLH family protein
ORGLA07G0144200.1bHLH family protein
ORGLA07G0180200.1bHLH family protein
ORGLA07G0232600.1bHLH family protein
ORGLA08G0018000.1bHLH family protein
ORGLA08G0041400.1bHLH family protein
ORGLA08G0137400.1bHLH family protein
ORGLA08G0155700.1bHLH family protein
ORGLA08G0157100.1bHLH family protein
ORGLA08G0160400.1bHLH family protein
ORGLA08G0163300.1bHLH family protein
ORGLA08G0164200.1bHLH family protein
ORGLA08G0174800.1bHLH family protein
ORGLA08G0194500.1bHLH family protein
ORGLA08G0199700.1bHLH family protein
ORGLA08G0221300.1bHLH family protein
ORGLA08G0226800.1bHLH family protein
ORGLA08G0237200.1bHLH family protein
ORGLA09G0076200.1bHLH family protein
ORGLA09G0096500.1bHLH family protein
ORGLA09G0101900.1bHLH family protein
ORGLA09G0105100.1bHLH family protein
ORGLA09G0105800.1bHLH family protein
ORGLA09G0112900.1bHLH family protein
ORGLA09G0119400.1bHLH family protein
ORGLA09G0124100.1bHLH family protein
ORGLA09G0131400.1bHLH family protein
ORGLA10G0001900.1bHLH family protein
ORGLA10G0067600.1bHLH family protein
ORGLA10G0079400.1bHLH family protein
ORGLA10G0079800.1bHLH family protein
ORGLA10G0124500.1bHLH family protein
ORGLA10G0133200.1bHLH family protein
ORGLA10G0146100.1bHLH family protein
ORGLA10G0168100.1bHLH family protein
ORGLA11G0035200.1bHLH family protein
ORGLA11G0077500.1bHLH family protein
ORGLA11G0103900.1bHLH family protein
ORGLA11G0129200.1bHLH family protein
ORGLA11G0160400.1bHLH family protein
ORGLA11G0161400.1bHLH family protein
ORGLA11G0169400.1bHLH family protein
ORGLA11G0204500.1bHLH family protein
ORGLA12G0114800.1bHLH family protein
ORGLA12G0149000.1bHLH family protein
ORGLA12G0157200.1bHLH family protein
ORGLA12G0170500.1bHLH family protein
ORGLA12G0196200.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250