PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza barthii
bHLH Family
Species TF ID Description
OBART01G00400.1bHLH family protein
OBART01G00600.1bHLH family protein
OBART01G00620.1bHLH family protein
OBART01G00850.1bHLH family protein
OBART01G03950.1bHLH family protein
OBART01G06120.1bHLH family protein
OBART01G06170.1bHLH family protein
OBART01G08590.1bHLH family protein
OBART01G11950.1bHLH family protein
OBART01G11950.2bHLH family protein
OBART01G11950.3bHLH family protein
OBART01G12290.1bHLH family protein
OBART01G17870.1bHLH family protein
OBART01G19850.1bHLH family protein
OBART01G20310.1bHLH family protein
OBART01G20350.1bHLH family protein
OBART01G28080.1bHLH family protein
OBART01G28250.1bHLH family protein
OBART01G32730.1bHLH family protein
OBART01G33360.1bHLH family protein
OBART01G36050.1bHLH family protein
OBART01G38370.1bHLH family protein
OBART01G40680.1bHLH family protein
OBART01G41700.1bHLH family protein
OBART01G41700.2bHLH family protein
OBART01G42600.1bHLH family protein
OBART01G44150.1bHLH family protein
OBART02G01220.1bHLH family protein
OBART02G01550.1bHLH family protein
OBART02G09660.1bHLH family protein
OBART02G11110.1bHLH family protein
OBART02G19940.1bHLH family protein
OBART02G19960.1bHLH family protein
OBART02G20940.1bHLH family protein
OBART02G20940.2bHLH family protein
OBART02G23210.1bHLH family protein
OBART02G23210.2bHLH family protein
OBART02G28630.1bHLH family protein
OBART02G29490.1bHLH family protein
OBART02G29800.1bHLH family protein
OBART02G30940.1bHLH family protein
OBART02G30940.2bHLH family protein
OBART02G30940.3bHLH family protein
OBART02G30940.4bHLH family protein
OBART02G30940.6bHLH family protein
OBART02G30940.7bHLH family protein
OBART02G32470.1bHLH family protein
OBART02G33270.1bHLH family protein
OBART02G35840.1bHLH family protein
OBART02G36490.1bHLH family protein
OBART03G01740.1bHLH family protein
OBART03G02840.1bHLH family protein
OBART03G05350.1bHLH family protein
OBART03G05370.1bHLH family protein
OBART03G06470.1bHLH family protein
OBART03G07520.1bHLH family protein
OBART03G09330.1bHLH family protein
OBART03G09470.1bHLH family protein
OBART03G11320.1bHLH family protein
OBART03G12630.1bHLH family protein
OBART03G19370.1bHLH family protein
OBART03G20100.1bHLH family protein
OBART03G26170.1bHLH family protein
OBART03G29020.1bHLH family protein
OBART03G29050.1bHLH family protein
OBART03G32580.1bHLH family protein
OBART03G32830.1bHLH family protein
OBART03G33610.1bHLH family protein
OBART03G34930.1bHLH family protein
OBART03G36360.1bHLH family protein
OBART03G36360.2bHLH family protein
OBART03G36360.3bHLH family protein
OBART03G36360.4bHLH family protein
OBART03G36360.5bHLH family protein
OBART03G36360.6bHLH family protein
OBART03G36360.7bHLH family protein
OBART03G36360.8bHLH family protein
OBART03G37400.1bHLH family protein
OBART03G37400.2bHLH family protein
OBART03G37850.1bHLH family protein
OBART04G06800.1bHLH family protein
OBART04G06800.2bHLH family protein
OBART04G06880.1bHLH family protein
OBART04G08520.1bHLH family protein
OBART04G10120.1bHLH family protein
OBART04G12870.1bHLH family protein
OBART04G12880.1bHLH family protein
OBART04G16900.1bHLH family protein
OBART04G21320.1bHLH family protein
OBART04G21320.2bHLH family protein
OBART04G21350.1bHLH family protein
OBART04G21370.1bHLH family protein
OBART04G21370.2bHLH family protein
OBART04G23490.1bHLH family protein
OBART04G23950.1bHLH family protein
OBART04G24870.1bHLH family protein
OBART04G25920.1bHLH family protein
OBART04G26980.1bHLH family protein
OBART05G00180.1bHLH family protein
OBART05G00180.2bHLH family protein
OBART05G04060.1bHLH family protein
OBART05G04450.1bHLH family protein
OBART05G06380.1bHLH family protein
OBART05G18950.1bHLH family protein
OBART05G21860.1bHLH family protein
OBART05G24340.1bHLH family protein
OBART05G27490.1bHLH family protein
OBART05G28280.1bHLH family protein
OBART06G04330.1bHLH family protein
OBART06G05420.1bHLH family protein
OBART06G06000.1bHLH family protein
OBART06G06000.2bHLH family protein
OBART06G10620.1bHLH family protein
OBART06G10620.2bHLH family protein
OBART06G16920.1bHLH family protein
OBART06G20960.1bHLH family protein
OBART06G27800.1bHLH family protein
OBART06G27860.1bHLH family protein
OBART07G02670.1bHLH family protein
OBART07G02670.2bHLH family protein
OBART07G05280.1bHLH family protein
OBART07G06150.1bHLH family protein
OBART07G07130.1bHLH family protein
OBART07G13960.1bHLH family protein
OBART07G17630.1bHLH family protein
OBART07G17630.2bHLH family protein
OBART07G18020.1bHLH family protein
OBART07G20550.1bHLH family protein
OBART07G23020.1bHLH family protein
OBART07G23020.2bHLH family protein
OBART08G04820.1bHLH family protein
OBART08G15650.1bHLH family protein
OBART08G18480.1bHLH family protein
OBART08G18760.1bHLH family protein
OBART08G18860.1bHLH family protein
OBART08G19860.1bHLH family protein
OBART08G21070.1bHLH family protein
OBART08G21870.1bHLH family protein
OBART08G22330.1bHLH family protein
OBART09G10360.1bHLH family protein
OBART09G12660.1bHLH family protein
OBART09G13210.1bHLH family protein
OBART09G13420.1bHLH family protein
OBART09G13780.1bHLH family protein
OBART09G13850.2bHLH family protein
OBART09G13850.3bHLH family protein
OBART09G13850.4bHLH family protein
OBART09G13850.5bHLH family protein
OBART09G14660.1bHLH family protein
OBART09G15400.1bHLH family protein
OBART09G15990.1bHLH family protein
OBART10G08120.1bHLH family protein
OBART10G09290.1bHLH family protein
OBART10G09330.1bHLH family protein
OBART10G17440.1bHLH family protein
OBART10G18190.1bHLH family protein
OBART10G18190.2bHLH family protein
OBART11G03790.1bHLH family protein
OBART11G12110.1bHLH family protein
OBART11G15260.1bHLH family protein
OBART11G19180.1bHLH family protein
OBART11G20580.1bHLH family protein
OBART12G13380.1bHLH family protein
OBART12G17400.1bHLH family protein
OBART12G17910.1bHLH family protein
OBART12G17940.1bHLH family protein
OBART12G17960.1bHLH family protein
OBART12G18000.1bHLH family protein
OBART12G18470.1bHLH family protein
OBART12G19700.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250