PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Oryza barthii
HD-ZIP Family
Species TF ID Description
OBART08G18330.1HD-ZIP family protein
OBART08G14710.1HD-ZIP family protein
OBART02G31160.1HD-ZIP family protein
OBART03G05300.1HD-ZIP family protein
OBART04G20760.1HD-ZIP family protein
OBART09G12140.1HD-ZIP family protein
OBART03G09400.1HD-ZIP family protein
OBART02G21000.1HD-ZIP family protein
OBART10G09370.1HD-ZIP family protein
OBART10G00190.1HD-ZIP family protein
OBART04G20320.1HD-ZIP family protein
OBART06G02540.1HD-ZIP family protein
OBART06G02560.1HD-ZIP family protein
OBART09G08380.1HD-ZIP family protein
OBART10G18570.1HD-ZIP family protein
OBART01G24330.1HD-ZIP family protein
OBART06G26110.1HD-ZIP family protein
OBART07G20030.1HD-ZIP family protein
OBART03G07110.1HD-ZIP family protein
OBART02G26000.1HD-ZIP family protein
OBART02G03860.1HD-ZIP family protein
OBART01G41950.1HD-ZIP family protein
OBART10G08140.1HD-ZIP family protein
OBART08G05070.2HD-ZIP family protein
OBART08G05070.1HD-ZIP family protein
OBART02G27630.1HD-ZIP family protein
OBART01G31750.1HD-ZIP family protein
OBART09G17090.1HD-ZIP family protein
OBART03G27200.1HD-ZIP family protein
OBART12G18630.1HD-ZIP family protein
OBART03G00720.2HD-ZIP family protein
OBART03G00720.1HD-ZIP family protein
OBART04G22070.1HD-ZIP family protein
OBART04G22070.2HD-ZIP family protein
OBART10G13430.1HD-ZIP family protein
OBART10G13430.2HD-ZIP family protein
OBART04G26630.1HD-ZIP family protein
OBART01G06400.4HD-ZIP family protein
OBART01G06400.2HD-ZIP family protein
OBART01G06400.5HD-ZIP family protein
OBART01G06400.3HD-ZIP family protein
OBART01G06400.1HD-ZIP family protein
OBART06G06830.1HD-ZIP family protein
OBART10G19440.1HD-ZIP family protein
OBART08G09450.1HD-ZIP family protein
OBART01G33600.1HD-ZIP family protein
OBART08G02270.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401