PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana tomentosiformis
WRKY Family
Species TF ID Description
XP_009586653.1WRKY family protein
XP_009587051.1WRKY family protein
XP_009587235.1WRKY family protein
XP_009587360.1WRKY family protein
XP_009588575.1WRKY family protein
XP_009588576.1WRKY family protein
XP_009589935.1WRKY family protein
XP_009590526.1WRKY family protein
XP_009591124.1WRKY family protein
XP_009591627.1WRKY family protein
XP_009591628.1WRKY family protein
XP_009591629.1WRKY family protein
XP_009591799.1WRKY family protein
XP_009593761.1WRKY family protein
XP_009593762.1WRKY family protein
XP_009594706.1WRKY family protein
XP_009594857.1WRKY family protein
XP_009595576.1WRKY family protein
XP_009595577.1WRKY family protein
XP_009595924.1WRKY family protein
XP_009597443.1WRKY family protein
XP_009597703.1WRKY family protein
XP_009598015.1WRKY family protein
XP_009598201.1WRKY family protein
XP_009598817.1WRKY family protein
XP_009598818.1WRKY family protein
XP_009598832.1WRKY family protein
XP_009598833.1WRKY family protein
XP_009599235.1WRKY family protein
XP_009600091.1WRKY family protein
XP_009600092.1WRKY family protein
XP_009600193.1WRKY family protein
XP_009600194.1WRKY family protein
XP_009600318.1WRKY family protein
XP_009600779.1WRKY family protein
XP_009600900.1WRKY family protein
XP_009601191.1WRKY family protein
XP_009601871.1WRKY family protein
XP_009602736.1WRKY family protein
XP_009603130.1WRKY family protein
XP_009603221.1WRKY family protein
XP_009604138.1WRKY family protein
XP_009604630.1WRKY family protein
XP_009604893.1WRKY family protein
XP_009605529.1WRKY family protein
XP_009606133.1WRKY family protein
XP_009606134.1WRKY family protein
XP_009606902.1WRKY family protein
XP_009606903.1WRKY family protein
XP_009606904.1WRKY family protein
XP_009607840.1WRKY family protein
XP_009608028.1WRKY family protein
XP_009608534.1WRKY family protein
XP_009609331.1WRKY family protein
XP_009609582.1WRKY family protein
XP_009609677.1WRKY family protein
XP_009610187.1WRKY family protein
XP_009610188.1WRKY family protein
XP_009610189.1WRKY family protein
XP_009610191.1WRKY family protein
XP_009610329.1WRKY family protein
XP_009610330.1WRKY family protein
XP_009610348.1WRKY family protein
XP_009610349.1WRKY family protein
XP_009613243.1WRKY family protein
XP_009613402.1WRKY family protein
XP_009614876.1WRKY family protein
XP_009615010.1WRKY family protein
XP_009615387.1WRKY family protein
XP_009615388.1WRKY family protein
XP_009615389.1WRKY family protein
XP_009615390.1WRKY family protein
XP_009615391.1WRKY family protein
XP_009615392.1WRKY family protein
XP_009615508.1WRKY family protein
XP_009615564.1WRKY family protein
XP_009615565.1WRKY family protein
XP_009615724.1WRKY family protein
XP_009616443.1WRKY family protein
XP_009616483.1WRKY family protein
XP_009616884.1WRKY family protein
XP_009617031.1WRKY family protein
XP_009617989.1WRKY family protein
XP_009618397.1WRKY family protein
XP_009619961.1WRKY family protein
XP_009621692.1WRKY family protein
XP_009622546.1WRKY family protein
XP_009623664.1WRKY family protein
XP_009624057.1WRKY family protein
XP_009624879.1WRKY family protein
XP_009625285.1WRKY family protein
XP_009625557.1WRKY family protein
XP_009625923.1WRKY family protein
XP_009626205.1WRKY family protein
XP_009626206.1WRKY family protein
XP_009626377.1WRKY family protein
XP_009626813.1WRKY family protein
XP_009627902.1WRKY family protein
XP_009628186.1WRKY family protein
XP_009628594.1WRKY family protein
XP_009628595.1WRKY family protein
XP_009628596.1WRKY family protein
XP_009628746.1WRKY family protein
XP_009628909.1WRKY family protein
XP_009628910.1WRKY family protein
XP_009628911.1WRKY family protein
XP_009629179.1WRKY family protein
XP_009630231.1WRKY family protein
XP_009630404.1WRKY family protein
XP_009630533.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701