PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana tomentosiformis
ERF Family
Species TF ID Description
XP_009586780.1ERF family protein
XP_009586781.1ERF family protein
XP_009586804.1ERF family protein
XP_009587236.1ERF family protein
XP_009587768.1ERF family protein
XP_009587769.1ERF family protein
XP_009587851.1ERF family protein
XP_009587871.1ERF family protein
XP_009588056.1ERF family protein
XP_009588133.1ERF family protein
XP_009588241.1ERF family protein
XP_009588287.1ERF family protein
XP_009589160.1ERF family protein
XP_009589439.1ERF family protein
XP_009589605.1ERF family protein
XP_009589826.1ERF family protein
XP_009589948.1ERF family protein
XP_009590142.1ERF family protein
XP_009590143.1ERF family protein
XP_009590609.1ERF family protein
XP_009590884.1ERF family protein
XP_009591034.1ERF family protein
XP_009591044.1ERF family protein
XP_009591053.1ERF family protein
XP_009591054.1ERF family protein
XP_009591318.1ERF family protein
XP_009591775.1ERF family protein
XP_009592010.1ERF family protein
XP_009592101.1ERF family protein
XP_009592157.1ERF family protein
XP_009592172.1ERF family protein
XP_009592286.1ERF family protein
XP_009592362.1ERF family protein
XP_009593007.1ERF family protein
XP_009593083.1ERF family protein
XP_009593203.1ERF family protein
XP_009593488.1ERF family protein
XP_009593489.1ERF family protein
XP_009593924.1ERF family protein
XP_009594350.1ERF family protein
XP_009594389.1ERF family protein
XP_009594472.1ERF family protein
XP_009594548.1ERF family protein
XP_009594905.1ERF family protein
XP_009595390.1ERF family protein
XP_009596026.1ERF family protein
XP_009596437.1ERF family protein
XP_009596565.1ERF family protein
XP_009596566.1ERF family protein
XP_009596664.1ERF family protein
XP_009597142.1ERF family protein
XP_009597158.1ERF family protein
XP_009597481.1ERF family protein
XP_009597482.1ERF family protein
XP_009597659.1ERF family protein
XP_009598034.1ERF family protein
XP_009598140.1ERF family protein
XP_009598275.1ERF family protein
XP_009598342.1ERF family protein
XP_009598443.1ERF family protein
XP_009598690.1ERF family protein
XP_009598696.1ERF family protein
XP_009598697.1ERF family protein
XP_009599132.1ERF family protein
XP_009599185.1ERF family protein
XP_009599489.1ERF family protein
XP_009599928.1ERF family protein
XP_009600167.1ERF family protein
XP_009601361.1ERF family protein
XP_009601836.1ERF family protein
XP_009602025.1ERF family protein
XP_009602361.1ERF family protein
XP_009603046.1ERF family protein
XP_009604256.1ERF family protein
XP_009604966.1ERF family protein
XP_009605490.1ERF family protein
XP_009605887.1ERF family protein
XP_009606089.1ERF family protein
XP_009606435.1ERF family protein
XP_009606597.1ERF family protein
XP_009606637.1ERF family protein
XP_009606945.1ERF family protein
XP_009606951.1ERF family protein
XP_009606952.1ERF family protein
XP_009607079.1ERF family protein
XP_009607270.1ERF family protein
XP_009607801.1ERF family protein
XP_009607861.1ERF family protein
XP_009608570.1ERF family protein
XP_009608915.1ERF family protein
XP_009609381.1ERF family protein
XP_009609421.1ERF family protein
XP_009609460.1ERF family protein
XP_009609461.1ERF family protein
XP_009609482.1ERF family protein
XP_009609535.1ERF family protein
XP_009609536.1ERF family protein
XP_009609579.1ERF family protein
XP_009609581.1ERF family protein
XP_009609806.1ERF family protein
XP_009610255.1ERF family protein
XP_009610256.1ERF family protein
XP_009610257.1ERF family protein
XP_009610259.1ERF family protein
XP_009610278.1ERF family protein
XP_009610624.1ERF family protein
XP_009611054.1ERF family protein
XP_009611402.1ERF family protein
XP_009611618.1ERF family protein
XP_009611619.1ERF family protein
XP_009611800.1ERF family protein
XP_009611801.1ERF family protein
XP_009611846.1ERF family protein
XP_009612863.1ERF family protein
XP_009613128.1ERF family protein
XP_009613405.1ERF family protein
XP_009613409.1ERF family protein
XP_009613454.1ERF family protein
XP_009613551.1ERF family protein
XP_009613570.1ERF family protein
XP_009613764.1ERF family protein
XP_009614214.1ERF family protein
XP_009614221.1ERF family protein
XP_009614418.1ERF family protein
XP_009614490.1ERF family protein
XP_009614946.1ERF family protein
XP_009615403.1ERF family protein
XP_009615540.1ERF family protein
XP_009615714.1ERF family protein
XP_009616468.1ERF family protein
XP_009616719.1ERF family protein
XP_009617210.1ERF family protein
XP_009617333.1ERF family protein
XP_009617605.1ERF family protein
XP_009617997.1ERF family protein
XP_009618026.1ERF family protein
XP_009618542.1ERF family protein
XP_009618993.1ERF family protein
XP_009619132.1ERF family protein
XP_009619193.1ERF family protein
XP_009619682.1ERF family protein
XP_009619700.1ERF family protein
XP_009619745.1ERF family protein
XP_009619856.1ERF family protein
XP_009619858.1ERF family protein
XP_009620060.1ERF family protein
XP_009620960.1ERF family protein
XP_009621025.1ERF family protein
XP_009621246.1ERF family protein
XP_009621305.1ERF family protein
XP_009621512.1ERF family protein
XP_009621762.1ERF family protein
XP_009621883.1ERF family protein
XP_009622476.1ERF family protein
XP_009622637.1ERF family protein
XP_009623988.1ERF family protein
XP_009624061.1ERF family protein
XP_009624342.1ERF family protein
XP_009624576.1ERF family protein
XP_009624600.1ERF family protein
XP_009624601.1ERF family protein
XP_009624644.1ERF family protein
XP_009624645.1ERF family protein
XP_009625172.1ERF family protein
XP_009625277.1ERF family protein
XP_009625479.1ERF family protein
XP_009625586.1ERF family protein
XP_009625877.1ERF family protein
XP_009625878.1ERF family protein
XP_009627498.1ERF family protein
XP_009627598.1ERF family protein
XP_009627746.1ERF family protein
XP_009628141.1ERF family protein
XP_009628238.1ERF family protein
XP_009628437.1ERF family protein
XP_009629720.1ERF family protein
XP_009629925.1ERF family protein
XP_009630285.1ERF family protein
XP_009630729.1ERF family protein
XP_009630856.1ERF family protein
XP_009631670.1ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102