PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana tabacum
NF-YA Family
Species TF ID Description
XP_016438502.1NF-YA family protein
XP_016438503.1NF-YA family protein
XP_016438504.1NF-YA family protein
XP_016438505.1NF-YA family protein
XP_016441195.1NF-YA family protein
XP_016441402.1NF-YA family protein
XP_016442485.1NF-YA family protein
XP_016443427.1NF-YA family protein
XP_016443428.1NF-YA family protein
XP_016445390.1NF-YA family protein
XP_016445397.1NF-YA family protein
XP_016445403.1NF-YA family protein
XP_016445406.1NF-YA family protein
XP_016445413.1NF-YA family protein
XP_016445419.1NF-YA family protein
XP_016447156.1NF-YA family protein
XP_016447157.1NF-YA family protein
XP_016447158.1NF-YA family protein
XP_016447159.1NF-YA family protein
XP_016447160.1NF-YA family protein
XP_016447161.1NF-YA family protein
XP_016447162.1NF-YA family protein
XP_016448259.1NF-YA family protein
XP_016456188.1NF-YA family protein
XP_016456190.1NF-YA family protein
XP_016456191.1NF-YA family protein
XP_016456192.1NF-YA family protein
XP_016456193.1NF-YA family protein
XP_016456194.1NF-YA family protein
XP_016462178.1NF-YA family protein
XP_016463189.1NF-YA family protein
XP_016464642.1NF-YA family protein
XP_016464643.1NF-YA family protein
XP_016464644.1NF-YA family protein
XP_016464645.1NF-YA family protein
XP_016464646.1NF-YA family protein
XP_016466591.1NF-YA family protein
XP_016466592.1NF-YA family protein
XP_016466593.1NF-YA family protein
XP_016466594.1NF-YA family protein
XP_016466595.1NF-YA family protein
XP_016469807.1NF-YA family protein
XP_016473523.1NF-YA family protein
XP_016473524.1NF-YA family protein
XP_016487785.1NF-YA family protein
XP_016487786.1NF-YA family protein
XP_016487787.1NF-YA family protein
XP_016487788.1NF-YA family protein
XP_016487789.1NF-YA family protein
XP_016487790.1NF-YA family protein
XP_016487791.1NF-YA family protein
XP_016488957.1NF-YA family protein
XP_016489448.1NF-YA family protein
XP_016489449.1NF-YA family protein
XP_016489451.1NF-YA family protein
XP_016496034.1NF-YA family protein
XP_016496035.1NF-YA family protein
XP_016496036.1NF-YA family protein
XP_016496037.1NF-YA family protein
XP_016496038.1NF-YA family protein
XP_016502905.1NF-YA family protein
XP_016508495.1NF-YA family protein
XP_016513896.1NF-YA family protein
XP_016513897.1NF-YA family protein
XP_016515661.1NF-YA family protein
XP_016515662.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982