PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana tabacum
FAR1 Family
Species TF ID Description
XP_016435093.1FAR1 family protein
XP_016435745.1FAR1 family protein
XP_016438171.1FAR1 family protein
XP_016438861.1FAR1 family protein
XP_016439116.1FAR1 family protein
XP_016439117.1FAR1 family protein
XP_016439118.1FAR1 family protein
XP_016439120.1FAR1 family protein
XP_016439307.1FAR1 family protein
XP_016440133.1FAR1 family protein
XP_016440134.1FAR1 family protein
XP_016440135.1FAR1 family protein
XP_016440137.1FAR1 family protein
XP_016441479.1FAR1 family protein
XP_016441729.1FAR1 family protein
XP_016441730.1FAR1 family protein
XP_016441731.1FAR1 family protein
XP_016443984.1FAR1 family protein
XP_016444397.1FAR1 family protein
XP_016446009.1FAR1 family protein
XP_016446010.1FAR1 family protein
XP_016446011.1FAR1 family protein
XP_016446595.1FAR1 family protein
XP_016446596.1FAR1 family protein
XP_016446598.1FAR1 family protein
XP_016449476.1FAR1 family protein
XP_016449477.1FAR1 family protein
XP_016449478.1FAR1 family protein
XP_016449479.1FAR1 family protein
XP_016449480.1FAR1 family protein
XP_016449482.1FAR1 family protein
XP_016449483.1FAR1 family protein
XP_016449484.1FAR1 family protein
XP_016450608.1FAR1 family protein
XP_016450609.1FAR1 family protein
XP_016450610.1FAR1 family protein
XP_016450611.1FAR1 family protein
XP_016450612.1FAR1 family protein
XP_016450613.1FAR1 family protein
XP_016451671.1FAR1 family protein
XP_016451885.1FAR1 family protein
XP_016454215.1FAR1 family protein
XP_016454216.1FAR1 family protein
XP_016454217.1FAR1 family protein
XP_016455342.1FAR1 family protein
XP_016455343.1FAR1 family protein
XP_016460554.1FAR1 family protein
XP_016460555.1FAR1 family protein
XP_016460556.1FAR1 family protein
XP_016460557.1FAR1 family protein
XP_016461330.1FAR1 family protein
XP_016461331.1FAR1 family protein
XP_016462421.1FAR1 family protein
XP_016463468.1FAR1 family protein
XP_016463874.1FAR1 family protein
XP_016463957.1FAR1 family protein
XP_016464498.1FAR1 family protein
XP_016464499.1FAR1 family protein
XP_016466671.1FAR1 family protein
XP_016467903.1FAR1 family protein
XP_016469116.1FAR1 family protein
XP_016470835.1FAR1 family protein
XP_016470842.1FAR1 family protein
XP_016475931.1FAR1 family protein
XP_016475932.1FAR1 family protein
XP_016477046.1FAR1 family protein
XP_016477354.1FAR1 family protein
XP_016478790.1FAR1 family protein
XP_016478794.1FAR1 family protein
XP_016478795.1FAR1 family protein
XP_016478796.1FAR1 family protein
XP_016479978.1FAR1 family protein
XP_016479979.1FAR1 family protein
XP_016479980.1FAR1 family protein
XP_016479981.1FAR1 family protein
XP_016481211.1FAR1 family protein
XP_016481212.1FAR1 family protein
XP_016481478.1FAR1 family protein
XP_016481996.1FAR1 family protein
XP_016481997.1FAR1 family protein
XP_016481998.1FAR1 family protein
XP_016481999.1FAR1 family protein
XP_016484077.1FAR1 family protein
XP_016484692.1FAR1 family protein
XP_016484723.1FAR1 family protein
XP_016485339.1FAR1 family protein
XP_016485340.1FAR1 family protein
XP_016485341.1FAR1 family protein
XP_016485342.1FAR1 family protein
XP_016486262.1FAR1 family protein
XP_016486263.1FAR1 family protein
XP_016486813.1FAR1 family protein
XP_016486814.1FAR1 family protein
XP_016487162.1FAR1 family protein
XP_016487163.1FAR1 family protein
XP_016487806.1FAR1 family protein
XP_016487807.1FAR1 family protein
XP_016487808.1FAR1 family protein
XP_016487809.1FAR1 family protein
XP_016487810.1FAR1 family protein
XP_016487811.1FAR1 family protein
XP_016487876.1FAR1 family protein
XP_016487877.1FAR1 family protein
XP_016487947.1FAR1 family protein
XP_016491088.1FAR1 family protein
XP_016491095.1FAR1 family protein
XP_016491102.1FAR1 family protein
XP_016491107.1FAR1 family protein
XP_016491113.1FAR1 family protein
XP_016491120.1FAR1 family protein
XP_016491126.1FAR1 family protein
XP_016491131.1FAR1 family protein
XP_016491135.1FAR1 family protein
XP_016491140.1FAR1 family protein
XP_016492611.1FAR1 family protein
XP_016492864.1FAR1 family protein
XP_016493358.1FAR1 family protein
XP_016494844.1FAR1 family protein
XP_016495821.1FAR1 family protein
XP_016495822.1FAR1 family protein
XP_016495823.1FAR1 family protein
XP_016495824.1FAR1 family protein
XP_016495825.1FAR1 family protein
XP_016495826.1FAR1 family protein
XP_016495827.1FAR1 family protein
XP_016495828.1FAR1 family protein
XP_016495829.1FAR1 family protein
XP_016496264.1FAR1 family protein
XP_016496265.1FAR1 family protein
XP_016496266.1FAR1 family protein
XP_016496267.1FAR1 family protein
XP_016496268.1FAR1 family protein
XP_016496269.1FAR1 family protein
XP_016496270.1FAR1 family protein
XP_016496271.1FAR1 family protein
XP_016499085.1FAR1 family protein
XP_016501486.1FAR1 family protein
XP_016504547.1FAR1 family protein
XP_016508482.1FAR1 family protein
XP_016508483.1FAR1 family protein
XP_016508484.1FAR1 family protein
XP_016508485.1FAR1 family protein
XP_016509197.1FAR1 family protein
XP_016509198.1FAR1 family protein
XP_016509199.1FAR1 family protein
XP_016509200.1FAR1 family protein
XP_016509201.1FAR1 family protein
XP_016509498.1FAR1 family protein
XP_016509681.1FAR1 family protein
XP_016509844.1FAR1 family protein
XP_016512038.1FAR1 family protein
XP_016512039.1FAR1 family protein
XP_016513209.1FAR1 family protein
XP_016513926.1FAR1 family protein
XP_016513927.1FAR1 family protein
XP_016513928.1FAR1 family protein
XP_016513929.1FAR1 family protein
XP_016513930.1FAR1 family protein
XP_016515263.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885