PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana tabacum
ERF Family
Species TF ID Description
XP_016432338.1ERF family protein
XP_016432386.1ERF family protein
XP_016432408.1ERF family protein
XP_016432455.1ERF family protein
XP_016432509.1ERF family protein
XP_016432636.1ERF family protein
XP_016433104.1ERF family protein
XP_016433398.1ERF family protein
XP_016434306.1ERF family protein
XP_016434837.1ERF family protein
XP_016434934.1ERF family protein
XP_016434973.1ERF family protein
XP_016435613.1ERF family protein
XP_016435615.1ERF family protein
XP_016435760.1ERF family protein
XP_016435827.1ERF family protein
XP_016435910.1ERF family protein
XP_016436102.1ERF family protein
XP_016436541.1ERF family protein
XP_016436953.1ERF family protein
XP_016437186.1ERF family protein
XP_016437637.1ERF family protein
XP_016438801.1ERF family protein
XP_016438849.1ERF family protein
XP_016439809.1ERF family protein
XP_016439810.1ERF family protein
XP_016439919.1ERF family protein
XP_016440103.1ERF family protein
XP_016440396.1ERF family protein
XP_016440397.1ERF family protein
XP_016440548.1ERF family protein
XP_016440909.1ERF family protein
XP_016440974.1ERF family protein
XP_016441026.1ERF family protein
XP_016441045.1ERF family protein
XP_016441364.1ERF family protein
XP_016441653.1ERF family protein
XP_016442410.1ERF family protein
XP_016442528.1ERF family protein
XP_016442529.1ERF family protein
XP_016442655.1ERF family protein
XP_016443748.1ERF family protein
XP_016443781.1ERF family protein
XP_016444470.1ERF family protein
XP_016444730.1ERF family protein
XP_016445024.1ERF family protein
XP_016445030.1ERF family protein
XP_016445188.1ERF family protein
XP_016445464.1ERF family protein
XP_016445500.1ERF family protein
XP_016446024.1ERF family protein
XP_016446449.1ERF family protein
XP_016446450.1ERF family protein
XP_016447100.1ERF family protein
XP_016447344.1ERF family protein
XP_016447448.1ERF family protein
XP_016447456.1ERF family protein
XP_016447462.1ERF family protein
XP_016448076.1ERF family protein
XP_016448393.1ERF family protein
XP_016448644.1ERF family protein
XP_016448710.1ERF family protein
XP_016449158.1ERF family protein
XP_016449238.1ERF family protein
XP_016449547.1ERF family protein
XP_016449577.1ERF family protein
XP_016449845.1ERF family protein
XP_016450672.1ERF family protein
XP_016450924.1ERF family protein
XP_016451267.1ERF family protein
XP_016451781.1ERF family protein
XP_016452272.1ERF family protein
XP_016452686.1ERF family protein
XP_016452918.1ERF family protein
XP_016453280.1ERF family protein
XP_016453436.1ERF family protein
XP_016453659.1ERF family protein
XP_016453709.1ERF family protein
XP_016453815.1ERF family protein
XP_016453834.1ERF family protein
XP_016453939.1ERF family protein
XP_016454360.1ERF family protein
XP_016454529.1ERF family protein
XP_016454891.1ERF family protein
XP_016455303.1ERF family protein
XP_016455711.1ERF family protein
XP_016455831.1ERF family protein
XP_016456149.1ERF family protein
XP_016456594.1ERF family protein
XP_016456981.1ERF family protein
XP_016457275.1ERF family protein
XP_016457383.1ERF family protein
XP_016458320.1ERF family protein
XP_016458345.1ERF family protein
XP_016459022.1ERF family protein
XP_016460165.1ERF family protein
XP_016460436.1ERF family protein
XP_016460453.1ERF family protein
XP_016460968.1ERF family protein
XP_016460970.1ERF family protein
XP_016460996.1ERF family protein
XP_016461010.1ERF family protein
XP_016461067.1ERF family protein
XP_016461280.1ERF family protein
XP_016461285.1ERF family protein
XP_016461559.1ERF family protein
XP_016462516.1ERF family protein
XP_016462558.1ERF family protein
XP_016462615.1ERF family protein
XP_016462719.1ERF family protein
XP_016462903.1ERF family protein
XP_016463526.1ERF family protein
XP_016464423.1ERF family protein
XP_016464424.1ERF family protein
XP_016465231.1ERF family protein
XP_016465391.1ERF family protein
XP_016465392.1ERF family protein
XP_016465556.1ERF family protein
XP_016465665.1ERF family protein
XP_016465672.1ERF family protein
XP_016465747.1ERF family protein
XP_016465777.1ERF family protein
XP_016465932.1ERF family protein
XP_016465991.1ERF family protein
XP_016466982.1ERF family protein
XP_016467384.1ERF family protein
XP_016467940.1ERF family protein
XP_016467956.1ERF family protein
XP_016468675.1ERF family protein
XP_016468771.1ERF family protein
XP_016468837.1ERF family protein
XP_016468873.1ERF family protein
XP_016469077.1ERF family protein
XP_016469246.1ERF family protein
XP_016469418.1ERF family protein
XP_016469567.1ERF family protein
XP_016469958.1ERF family protein
XP_016470184.1ERF family protein
XP_016470252.1ERF family protein
XP_016470253.1ERF family protein
XP_016470254.1ERF family protein
XP_016470931.1ERF family protein
XP_016471898.1ERF family protein
XP_016472071.1ERF family protein
XP_016472235.1ERF family protein
XP_016472259.1ERF family protein
XP_016472267.1ERF family protein
XP_016472275.1ERF family protein
XP_016472294.1ERF family protein
XP_016472543.1ERF family protein
XP_016472690.1ERF family protein
XP_016473047.1ERF family protein
XP_016473386.1ERF family protein
XP_016473388.1ERF family protein
XP_016473393.1ERF family protein
XP_016473785.1ERF family protein
XP_016474865.1ERF family protein
XP_016474894.1ERF family protein
XP_016474916.1ERF family protein
XP_016475325.1ERF family protein
XP_016475341.1ERF family protein
XP_016475503.1ERF family protein
XP_016475770.1ERF family protein
XP_016475776.1ERF family protein
XP_016476340.1ERF family protein
XP_016476348.1ERF family protein
XP_016476387.1ERF family protein
XP_016476415.1ERF family protein
XP_016476518.1ERF family protein
XP_016476774.1ERF family protein
XP_016476955.1ERF family protein
XP_016476956.1ERF family protein
XP_016476957.1ERF family protein
XP_016476958.1ERF family protein
XP_016476959.1ERF family protein
XP_016476960.1ERF family protein
XP_016477230.1ERF family protein
XP_016478305.1ERF family protein
XP_016478342.1ERF family protein
XP_016478716.1ERF family protein
XP_016478763.1ERF family protein
XP_016479249.1ERF family protein
XP_016479524.1ERF family protein
XP_016479743.1ERF family protein
XP_016479822.1ERF family protein
XP_016480146.1ERF family protein
XP_016480477.1ERF family protein
XP_016480696.1ERF family protein
XP_016480744.1ERF family protein
XP_016480849.1ERF family protein
XP_016481010.1ERF family protein
XP_016481012.1ERF family protein
XP_016481040.1ERF family protein
XP_016481253.1ERF family protein
XP_016481687.1ERF family protein
XP_016482001.1ERF family protein
XP_016483059.1ERF family protein
XP_016483068.1ERF family protein
XP_016483203.1ERF family protein
XP_016483289.1ERF family protein
XP_016483897.1ERF family protein
XP_016484123.1ERF family protein
XP_016484272.1ERF family protein
XP_016484344.1ERF family protein
XP_016484531.1ERF family protein
XP_016484767.1ERF family protein
XP_016484768.1ERF family protein
XP_016485293.1ERF family protein
XP_016485379.1ERF family protein
XP_016485767.1ERF family protein
XP_016486086.1ERF family protein
XP_016486540.1ERF family protein
XP_016487471.1ERF family protein
XP_016487472.1ERF family protein
XP_016487564.1ERF family protein
XP_016487864.1ERF family protein
XP_016487974.1ERF family protein
XP_016487979.1ERF family protein
XP_016488142.1ERF family protein
XP_016488144.1ERF family protein
XP_016488485.1ERF family protein
XP_016488545.1ERF family protein
XP_016488798.1ERF family protein
XP_016488917.1ERF family protein
XP_016489228.1ERF family protein
XP_016489782.1ERF family protein
XP_016489848.1ERF family protein
XP_016490268.1ERF family protein
XP_016490378.1ERF family protein
XP_016490911.1ERF family protein
XP_016491234.1ERF family protein
XP_016491248.1ERF family protein
XP_016491251.1ERF family protein
XP_016491288.1ERF family protein
XP_016491714.1ERF family protein
XP_016491715.1ERF family protein
XP_016492019.1ERF family protein
XP_016492134.1ERF family protein
XP_016492135.1ERF family protein
XP_016492374.1ERF family protein
XP_016492543.1ERF family protein
XP_016493325.1ERF family protein
XP_016493944.1ERF family protein
XP_016494298.1ERF family protein
XP_016494706.1ERF family protein
XP_016495062.1ERF family protein
XP_016495179.1ERF family protein
XP_016495741.1ERF family protein
XP_016495794.1ERF family protein
XP_016496200.1ERF family protein
XP_016496242.1ERF family protein
XP_016496384.1ERF family protein
XP_016496753.1ERF family protein
XP_016496938.1ERF family protein
XP_016497010.1ERF family protein
XP_016497089.1ERF family protein
XP_016497238.1ERF family protein
XP_016497257.1ERF family protein
XP_016497315.1ERF family protein
XP_016497545.1ERF family protein
XP_016497649.1ERF family protein
XP_016497815.1ERF family protein
XP_016497816.1ERF family protein
XP_016497817.1ERF family protein
XP_016497877.1ERF family protein
XP_016497887.1ERF family protein
XP_016498953.1ERF family protein
XP_016499345.1ERF family protein
XP_016499871.1ERF family protein
XP_016499931.1ERF family protein
XP_016499932.1ERF family protein
XP_016500182.1ERF family protein
XP_016500183.1ERF family protein
XP_016500458.1ERF family protein
XP_016500912.1ERF family protein
XP_016500913.1ERF family protein
XP_016500973.1ERF family protein
XP_016501064.1ERF family protein
XP_016501349.1ERF family protein
XP_016501550.1ERF family protein
XP_016502425.1ERF family protein
XP_016502757.1ERF family protein
XP_016502765.1ERF family protein
XP_016503153.1ERF family protein
XP_016503157.1ERF family protein
XP_016503257.1ERF family protein
XP_016503258.1ERF family protein
XP_016503259.1ERF family protein
XP_016503578.1ERF family protein
XP_016504100.1ERF family protein
XP_016504445.1ERF family protein
XP_016504526.1ERF family protein
XP_016504621.1ERF family protein
XP_016504673.1ERF family protein
XP_016504834.1ERF family protein
XP_016504837.1ERF family protein
XP_016505072.1ERF family protein
XP_016505621.1ERF family protein
XP_016506458.1ERF family protein
XP_016506469.1ERF family protein
XP_016506818.1ERF family protein
XP_016506871.1ERF family protein
XP_016506872.1ERF family protein
XP_016507098.1ERF family protein
XP_016507154.1ERF family protein
XP_016507356.1ERF family protein
XP_016507363.1ERF family protein
XP_016507382.1ERF family protein
XP_016507834.1ERF family protein
XP_016507835.1ERF family protein
XP_016508571.1ERF family protein
XP_016510019.1ERF family protein
XP_016510115.1ERF family protein
XP_016510284.1ERF family protein
XP_016510285.1ERF family protein
XP_016510932.1ERF family protein
XP_016511042.1ERF family protein
XP_016511096.1ERF family protein
XP_016511097.1ERF family protein
XP_016511488.1ERF family protein
XP_016511718.1ERF family protein
XP_016511764.1ERF family protein
XP_016511921.1ERF family protein
XP_016512115.1ERF family protein
XP_016512157.1ERF family protein
XP_016512583.1ERF family protein
XP_016512598.1ERF family protein
XP_016512690.1ERF family protein
XP_016512703.1ERF family protein
XP_016512826.1ERF family protein
XP_016513393.1ERF family protein
XP_016514028.1ERF family protein
XP_016514523.1ERF family protein
XP_016515225.1ERF family protein
XP_016515494.1ERF family protein
XP_016515585.1ERF family protein
XP_016516016.1ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102