PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana tabacum
AP2 Family
Species TF ID Description
XP_016432764.1AP2 family protein
XP_016432773.1AP2 family protein
XP_016432779.1AP2 family protein
XP_016432907.1AP2 family protein
XP_016438555.1AP2 family protein
XP_016442336.1AP2 family protein
XP_016442764.1AP2 family protein
XP_016442765.1AP2 family protein
XP_016442766.1AP2 family protein
XP_016442767.1AP2 family protein
XP_016442778.1AP2 family protein
XP_016450856.1AP2 family protein
XP_016452614.1AP2 family protein
XP_016457719.1AP2 family protein
XP_016458466.1AP2 family protein
XP_016458467.1AP2 family protein
XP_016458468.1AP2 family protein
XP_016459641.1AP2 family protein
XP_016459840.1AP2 family protein
XP_016459841.1AP2 family protein
XP_016460979.1AP2 family protein
XP_016460980.1AP2 family protein
XP_016460981.1AP2 family protein
XP_016462704.1AP2 family protein
XP_016466578.1AP2 family protein
XP_016467673.1AP2 family protein
XP_016467674.1AP2 family protein
XP_016467675.1AP2 family protein
XP_016476467.1AP2 family protein
XP_016476468.1AP2 family protein
XP_016476469.1AP2 family protein
XP_016476471.1AP2 family protein
XP_016476472.1AP2 family protein
XP_016480504.1AP2 family protein
XP_016480505.1AP2 family protein
XP_016482517.1AP2 family protein
XP_016482629.1AP2 family protein
XP_016482630.1AP2 family protein
XP_016483586.1AP2 family protein
XP_016483687.1AP2 family protein
XP_016483746.1AP2 family protein
XP_016485713.1AP2 family protein
XP_016485715.1AP2 family protein
XP_016487804.1AP2 family protein
XP_016488066.1AP2 family protein
XP_016488067.1AP2 family protein
XP_016488068.1AP2 family protein
XP_016489488.1AP2 family protein
XP_016489489.1AP2 family protein
XP_016491022.1AP2 family protein
XP_016491201.1AP2 family protein
XP_016491202.1AP2 family protein
XP_016491203.1AP2 family protein
XP_016491204.1AP2 family protein
XP_016491205.1AP2 family protein
XP_016491206.1AP2 family protein
XP_016491207.1AP2 family protein
XP_016491208.1AP2 family protein
XP_016493916.1AP2 family protein
XP_016494296.1AP2 family protein
XP_016494297.1AP2 family protein
XP_016494847.1AP2 family protein
XP_016495732.1AP2 family protein
XP_016495796.1AP2 family protein
XP_016495797.1AP2 family protein
XP_016497518.1AP2 family protein
XP_016497688.1AP2 family protein
XP_016499635.1AP2 family protein
XP_016500454.1AP2 family protein
XP_016500455.1AP2 family protein
XP_016501408.1AP2 family protein
XP_016501410.1AP2 family protein
XP_016502850.1AP2 family protein
XP_016502851.1AP2 family protein
XP_016504355.1AP2 family protein
XP_016506032.1AP2 family protein
XP_016512702.1AP2 family protein
XP_016477494.1AP2 family protein
XP_016440480.1AP2 family protein
XP_016499643.1AP2 family protein
XP_016475255.1AP2 family protein
XP_016475254.1AP2 family protein
XP_016501409.1AP2 family protein
XP_016482518.1AP2 family protein
XP_016432786.1AP2 family protein
XP_016460982.1AP2 family protein
XP_016454720.1AP2 family protein
XP_016454719.1AP2 family protein
XP_016495733.1AP2 family protein
XP_016474866.1AP2 family protein
XP_016447562.1AP2 family protein
XP_016452443.1AP2 family protein
XP_016468120.1AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102