PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana sylvestris
WRKY Family
Species TF ID Description
XP_009758175.1WRKY family protein
XP_009758490.1WRKY family protein
XP_009758491.1WRKY family protein
XP_009758579.1WRKY family protein
XP_009760855.1WRKY family protein
XP_009760864.1WRKY family protein
XP_009763636.1WRKY family protein
XP_009764098.1WRKY family protein
XP_009764099.1WRKY family protein
XP_009764100.1WRKY family protein
XP_009764101.1WRKY family protein
XP_009764102.1WRKY family protein
XP_009764103.1WRKY family protein
XP_009764104.1WRKY family protein
XP_009764184.1WRKY family protein
XP_009764202.1WRKY family protein
XP_009764262.1WRKY family protein
XP_009764282.1WRKY family protein
XP_009764599.1WRKY family protein
XP_009764801.1WRKY family protein
XP_009765461.1WRKY family protein
XP_009766292.1WRKY family protein
XP_009767666.1WRKY family protein
XP_009768106.1WRKY family protein
XP_009768533.1WRKY family protein
XP_009768958.1WRKY family protein
XP_009768977.1WRKY family protein
XP_009768979.1WRKY family protein
XP_009769736.1WRKY family protein
XP_009769737.1WRKY family protein
XP_009769738.1WRKY family protein
XP_009769739.1WRKY family protein
XP_009770697.1WRKY family protein
XP_009772110.1WRKY family protein
XP_009772378.1WRKY family protein
XP_009773393.1WRKY family protein
XP_009773394.1WRKY family protein
XP_009773395.1WRKY family protein
XP_009773396.1WRKY family protein
XP_009774253.1WRKY family protein
XP_009775430.1WRKY family protein
XP_009775524.1WRKY family protein
XP_009775525.1WRKY family protein
XP_009775526.1WRKY family protein
XP_009775593.1WRKY family protein
XP_009775710.1WRKY family protein
XP_009775814.1WRKY family protein
XP_009775815.1WRKY family protein
XP_009776126.1WRKY family protein
XP_009776375.1WRKY family protein
XP_009776376.1WRKY family protein
XP_009776377.1WRKY family protein
XP_009776873.1WRKY family protein
XP_009778379.1WRKY family protein
XP_009778997.1WRKY family protein
XP_009778998.1WRKY family protein
XP_009779355.1WRKY family protein
XP_009780429.1WRKY family protein
XP_009781810.1WRKY family protein
XP_009781934.1WRKY family protein
XP_009782635.1WRKY family protein
XP_009782637.1WRKY family protein
XP_009784443.1WRKY family protein
XP_009784444.1WRKY family protein
XP_009784445.1WRKY family protein
XP_009784446.1WRKY family protein
XP_009785573.1WRKY family protein
XP_009785821.1WRKY family protein
XP_009786892.1WRKY family protein
XP_009788059.1WRKY family protein
XP_009788556.1WRKY family protein
XP_009789029.1WRKY family protein
XP_009789114.1WRKY family protein
XP_009789115.1WRKY family protein
XP_009789246.1WRKY family protein
XP_009790285.1WRKY family protein
XP_009790361.1WRKY family protein
XP_009790461.1WRKY family protein
XP_009790875.1WRKY family protein
XP_009790876.1WRKY family protein
XP_009791230.1WRKY family protein
XP_009791231.1WRKY family protein
XP_009791232.1WRKY family protein
XP_009793195.1WRKY family protein
XP_009793203.1WRKY family protein
XP_009793213.1WRKY family protein
XP_009793240.1WRKY family protein
XP_009793241.1WRKY family protein
XP_009793242.1WRKY family protein
XP_009793244.1WRKY family protein
XP_009793854.1WRKY family protein
XP_009793883.1WRKY family protein
XP_009794073.1WRKY family protein
XP_009794188.1WRKY family protein
XP_009797802.1WRKY family protein
XP_009797862.1WRKY family protein
XP_009797864.1WRKY family protein
XP_009798626.1WRKY family protein
XP_009798860.1WRKY family protein
XP_009800925.1WRKY family protein
XP_009800929.1WRKY family protein
XP_009800949.1WRKY family protein
XP_009801586.1WRKY family protein
XP_009802036.1WRKY family protein
XP_009802037.1WRKY family protein
XP_009802478.1WRKY family protein
XP_009804327.1WRKY family protein
XP_009804328.1WRKY family protein
XP_009804436.1WRKY family protein
XP_009804478.1WRKY family protein
XP_009804801.1WRKY family protein
XP_009804802.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701