PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Nicotiana sylvestris
NF-YA Family
Species TF ID Description
XP_009759697.1NF-YA family protein
XP_009759698.1NF-YA family protein
XP_009759699.1NF-YA family protein
XP_009759700.1NF-YA family protein
XP_009759701.1NF-YA family protein
XP_009759702.1NF-YA family protein
XP_009761217.1NF-YA family protein
XP_009761218.1NF-YA family protein
XP_009761897.1NF-YA family protein
XP_009767409.1NF-YA family protein
XP_009767410.1NF-YA family protein
XP_009767411.1NF-YA family protein
XP_009767412.1NF-YA family protein
XP_009767513.1NF-YA family protein
XP_009767514.1NF-YA family protein
XP_009769785.1NF-YA family protein
XP_009769786.1NF-YA family protein
XP_009770986.1NF-YA family protein
XP_009778037.1NF-YA family protein
XP_009780662.1NF-YA family protein
XP_009782268.1NF-YA family protein
XP_009793846.1NF-YA family protein
XP_009793847.1NF-YA family protein
XP_009793848.1NF-YA family protein
XP_009793849.1NF-YA family protein
XP_009793850.1NF-YA family protein
XP_009793851.1NF-YA family protein
XP_009801470.1NF-YA family protein
XP_009802925.1NF-YA family protein
XP_009802926.1NF-YA family protein
XP_009802927.1NF-YA family protein
XP_009802928.1NF-YA family protein
XP_009802929.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982