PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana sylvestris
ARF Family
Species TF ID Description
XP_009757615.1ARF family protein
XP_009757616.1ARF family protein
XP_009762809.1ARF family protein
XP_009762810.1ARF family protein
XP_009764747.1ARF family protein
XP_009764748.1ARF family protein
XP_009768741.1ARF family protein
XP_009769534.1ARF family protein
XP_009769535.1ARF family protein
XP_009769536.1ARF family protein
XP_009769542.1ARF family protein
XP_009769543.1ARF family protein
XP_009773406.1ARF family protein
XP_009773407.1ARF family protein
XP_009773408.1ARF family protein
XP_009773409.1ARF family protein
XP_009773411.1ARF family protein
XP_009778804.1ARF family protein
XP_009778805.1ARF family protein
XP_009778806.1ARF family protein
XP_009779766.1ARF family protein
XP_009784518.1ARF family protein
XP_009784519.1ARF family protein
XP_009786487.1ARF family protein
XP_009786488.1ARF family protein
XP_009786489.1ARF family protein
XP_009786490.1ARF family protein
XP_009786798.1ARF family protein
XP_009786799.1ARF family protein
XP_009789648.1ARF family protein
XP_009791106.1ARF family protein
XP_009791842.1ARF family protein
XP_009797447.1ARF family protein
XP_009797608.1ARF family protein
XP_009797609.1ARF family protein
XP_009797612.1ARF family protein
XP_009797614.1ARF family protein
XP_009797615.1ARF family protein
XP_009797616.1ARF family protein
XP_009797617.1ARF family protein
XP_009797618.1ARF family protein
XP_009797619.1ARF family protein
XP_009798135.1ARF family protein
XP_009798136.1ARF family protein
XP_009799485.1ARF family protein
XP_009803255.1ARF family protein
XP_009803256.1ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969