PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana sylvestris
AP2 Family
Species TF ID Description
XP_009757386.1AP2 family protein
XP_009761562.1AP2 family protein
XP_009763770.1AP2 family protein
XP_009764167.1AP2 family protein
XP_009766452.1AP2 family protein
XP_009767489.1AP2 family protein
XP_009769089.1AP2 family protein
XP_009769091.1AP2 family protein
XP_009769992.1AP2 family protein
XP_009769993.1AP2 family protein
XP_009769994.1AP2 family protein
XP_009769995.1AP2 family protein
XP_009769996.1AP2 family protein
XP_009770281.1AP2 family protein
XP_009770282.1AP2 family protein
XP_009770283.1AP2 family protein
XP_009771233.1AP2 family protein
XP_009774530.1AP2 family protein
XP_009776255.1AP2 family protein
XP_009780790.1AP2 family protein
XP_009782007.1AP2 family protein
XP_009782008.1AP2 family protein
XP_009782009.1AP2 family protein
XP_009782436.1AP2 family protein
XP_009782437.1AP2 family protein
XP_009782438.1AP2 family protein
XP_009783399.1AP2 family protein
XP_009783400.1AP2 family protein
XP_009783619.1AP2 family protein
XP_009784819.1AP2 family protein
XP_009784821.1AP2 family protein
XP_009793520.1AP2 family protein
XP_009799135.1AP2 family protein
XP_009799136.1AP2 family protein
XP_009799137.1AP2 family protein
XP_009801491.1AP2 family protein
XP_009801579.1AP2 family protein
XP_009801580.1AP2 family protein
XP_009804919.1AP2 family protein
XP_009804920.1AP2 family protein
XP_009804921.1AP2 family protein
XP_009783849.1AP2 family protein
XP_009786832.1AP2 family protein
XP_009769090.1AP2 family protein
XP_009772738.1AP2 family protein
XP_009772737.1AP2 family protein
XP_009784820.1AP2 family protein
XP_009782010.1AP2 family protein
XP_009757729.1AP2 family protein
XP_009783133.1AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102