PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nelumbo nucifera
WRKY Family
Species TF ID Description
NNU_000764-RAWRKY family protein
NNU_000906-RAWRKY family protein
NNU_000937-RAWRKY family protein
NNU_001380-RAWRKY family protein
NNU_002747-RAWRKY family protein
NNU_003142-RAWRKY family protein
NNU_004050-RAWRKY family protein
NNU_004768-RAWRKY family protein
NNU_004769-RAWRKY family protein
NNU_005007-RAWRKY family protein
NNU_005172-RAWRKY family protein
NNU_005293-RAWRKY family protein
NNU_005350-RAWRKY family protein
NNU_005576-RAWRKY family protein
NNU_007278-RAWRKY family protein
NNU_007649-RAWRKY family protein
NNU_007725-RAWRKY family protein
NNU_008364-RAWRKY family protein
NNU_008419-RAWRKY family protein
NNU_008704-RAWRKY family protein
NNU_009014-RAWRKY family protein
NNU_009041-RAWRKY family protein
NNU_009557-RAWRKY family protein
NNU_010097-RAWRKY family protein
NNU_010128-RAWRKY family protein
NNU_010321-RAWRKY family protein
NNU_010326-RAWRKY family protein
NNU_010416-RAWRKY family protein
NNU_010692-RAWRKY family protein
NNU_011033-RAWRKY family protein
NNU_011577-RAWRKY family protein
NNU_012242-RAWRKY family protein
NNU_012815-RAWRKY family protein
NNU_013081-RAWRKY family protein
NNU_013102-RAWRKY family protein
NNU_013507-RAWRKY family protein
NNU_013509-RAWRKY family protein
NNU_014445-RAWRKY family protein
NNU_014473-RAWRKY family protein
NNU_014662-RAWRKY family protein
NNU_014805-RAWRKY family protein
NNU_015314-RAWRKY family protein
NNU_015799-RAWRKY family protein
NNU_015800-RAWRKY family protein
NNU_018270-RAWRKY family protein
NNU_018552-RAWRKY family protein
NNU_019387-RAWRKY family protein
NNU_019405-RAWRKY family protein
NNU_019808-RAWRKY family protein
NNU_020713-RAWRKY family protein
NNU_020936-RAWRKY family protein
NNU_021524-RAWRKY family protein
NNU_021907-RAWRKY family protein
NNU_022759-RAWRKY family protein
NNU_022872-RAWRKY family protein
NNU_023323-RAWRKY family protein
NNU_023785-RAWRKY family protein
NNU_024102-RAWRKY family protein
NNU_024662-RAWRKY family protein
NNU_024663-RAWRKY family protein
NNU_025262-RAWRKY family protein
NNU_025395-RAWRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701