PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nelumbo nucifera
ERF Family
Species TF ID Description
NNU_001121-RAERF family protein
NNU_001227-RAERF family protein
NNU_001736-RAERF family protein
NNU_002048-RAERF family protein
NNU_002081-RAERF family protein
NNU_002384-RAERF family protein
NNU_002386-RAERF family protein
NNU_002894-RAERF family protein
NNU_003242-RAERF family protein
NNU_003274-RAERF family protein
NNU_003719-RAERF family protein
NNU_003917-RAERF family protein
NNU_003945-RAERF family protein
NNU_004272-RAERF family protein
NNU_004512-RAERF family protein
NNU_004758-RAERF family protein
NNU_004953-RAERF family protein
NNU_005082-RAERF family protein
NNU_005476-RAERF family protein
NNU_005886-RAERF family protein
NNU_005977-RAERF family protein
NNU_006170-RAERF family protein
NNU_006826-RAERF family protein
NNU_006827-RAERF family protein
NNU_007747-RAERF family protein
NNU_007903-RAERF family protein
NNU_008087-RAERF family protein
NNU_008734-RAERF family protein
NNU_008735-RAERF family protein
NNU_008778-RAERF family protein
NNU_009154-RAERF family protein
NNU_009155-RAERF family protein
NNU_009641-RAERF family protein
NNU_009642-RAERF family protein
NNU_009715-RAERF family protein
NNU_009718-RAERF family protein
NNU_009905-RAERF family protein
NNU_010073-RAERF family protein
NNU_010265-RAERF family protein
NNU_010390-RAERF family protein
NNU_010434-RAERF family protein
NNU_010532-RAERF family protein
NNU_010561-RAERF family protein
NNU_010879-RAERF family protein
NNU_010880-RAERF family protein
NNU_010881-RAERF family protein
NNU_011592-RAERF family protein
NNU_011665-RAERF family protein
NNU_012184-RAERF family protein
NNU_012185-RAERF family protein
NNU_012186-RAERF family protein
NNU_012187-RAERF family protein
NNU_012654-RAERF family protein
NNU_012866-RAERF family protein
NNU_012883-RAERF family protein
NNU_013149-RAERF family protein
NNU_013166-RAERF family protein
NNU_013581-RAERF family protein
NNU_014220-RAERF family protein
NNU_015221-RAERF family protein
NNU_015475-RAERF family protein
NNU_015476-RAERF family protein
NNU_015711-RAERF family protein
NNU_016354-RAERF family protein
NNU_016649-RAERF family protein
NNU_017150-RAERF family protein
NNU_017152-RAERF family protein
NNU_017553-RAERF family protein
NNU_017634-RAERF family protein
NNU_018165-RAERF family protein
NNU_018197-RAERF family protein
NNU_018198-RAERF family protein
NNU_018298-RAERF family protein
NNU_018406-RAERF family protein
NNU_018848-RAERF family protein
NNU_018849-RAERF family protein
NNU_018850-RAERF family protein
NNU_018851-RAERF family protein
NNU_018852-RAERF family protein
NNU_019231-RAERF family protein
NNU_019233-RAERF family protein
NNU_020935-RAERF family protein
NNU_021175-RAERF family protein
NNU_021176-RAERF family protein
NNU_021532-RAERF family protein
NNU_021622-RAERF family protein
NNU_022363-RAERF family protein
NNU_022661-RAERF family protein
NNU_022723-RAERF family protein
NNU_023107-RAERF family protein
NNU_023109-RAERF family protein
NNU_023626-RAERF family protein
NNU_023703-RAERF family protein
NNU_024231-RAERF family protein
NNU_024397-RAERF family protein
NNU_024742-RAERF family protein
NNU_024906-RAERF family protein
NNU_025033-RAERF family protein
NNU_025087-RAERF family protein
NNU_025355-RAERF family protein
NNU_025916-RAERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102