PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana benthamiana
WOX Family
Species TF ID Description
Niben101Scf07451g01002.1WOX family protein
Niben101Scf08653g06018.1WOX family protein
Niben101Scf00170g00005.1WOX family protein
Niben101Scf05506g06001.1WOX family protein
Niben101Scf01337g03002.1WOX family protein
Niben101Scf03735g01005.1WOX family protein
Niben101Scf01154g11014.1WOX family protein
Niben101Scf06267g03011.1WOX family protein
Niben101Scf07275g02001.1WOX family protein
Niben101Scf01094g02006.1WOX family protein
Niben101Scf06027g00002.1WOX family protein
Niben101Scf08673g02020.1WOX family protein
Niben101Scf01154g08005.1WOX family protein
Niben101Scf06590g02002.1WOX family protein
Niben101Scf00482g03010.1WOX family protein
Niben101Scf12526g00012.1WOX family protein
Niben101Scf00170g02001.1WOX family protein
Niben101Scf03689g01013.1WOX family protein
Niben101Scf02369g00003.1WOX family protein
Niben101Scf02041g05003.1WOX family protein
Niben101Scf03673g02007.1WOX family protein
Niben101Scf07493g01001.1WOX family protein
Niben101Scf03751g00003.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401


The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590